盐酸达克罗宁凝胶剂的研制  

A Study on the Preparation of Dyclonine Hydrochloride Gels

作　　者：杨丽[1] 杨敏[2] 杨文展[1] 赵猛 霍永志 毕殿洲[1] 

机构地区：[1]沈阳药科大学药学系,沈阳110015 [2]兰州铁路局玉门铁路医院,玉门735201

出　　处：《沈阳药科大学学报》2000年第3期174-175,187,共3页Journal of Shenyang Pharmaceutical University

摘　　要：选择卡波沫为主要基质 ,以 5 %聚山梨酯 80为增溶剂 ,制备了盐酸达克罗宁水凝胶剂 .用紫外法测定该凝胶剂的主药含量 ,平均回收率为 10 0 9% ,RSD为 0 85 % 。Dyclonine hydrochloride gels were prepared by the combination of the drug,5% Tween 80 as the solubilizing agent and the base composed of Carbomer.A UV spectrophotometry was used for the quantitative determination of dyclonine hydrochloride in the gels.The average recovery was 100 9%, and RSD ,0 58%.The drug release pattern from the gels was in accord with the Higuchi equation.

关 键 词：盐酸达克罗宁 凝胶剂 紫外法 释放规律 

分 类 号：R971.2[医药卫生—药品]