赤芍提取物的吸湿性及不同提取工艺和辅料对其吸湿性的影响  

Moisture absorption of Paeoniae Radix Rubra extract and influence of different extractive process and adjuvants

作　　者：皮佳鑫[1] 高旭[1] 于悦[1] 王亚静[1] 刘虹[1] 姜佳 

机构地区：[1]天津中医药大学,天津市现代中药重点实验室-省部共建国家重点实验室培育基地,现代中药发现与制剂技术教育工程研究中心,300193

出　　处：《天津中医药大学学报》2012年第4期221-224,共4页Journal of Tianjin University of Traditional Chinese Medicine

基　　金：国家科技重大专项"重大新药创制"项目(2012ZX09304007)

摘　　要：[目的]研究赤芍提取物的吸湿性,探讨提取工艺和辅料对赤芍提取物吸湿性的影响。[方法]采用粉末吸湿法,测定样品的吸湿率;以吸湿初速度、吸湿加速度、平衡吸湿时间、平衡吸湿量、临界相对湿度等吸湿参数为指标,考察不同提取工艺下赤芍提取物的吸湿性及辅料对其的影响。[结果]提取过程中经过大孔吸附树脂处理和加入一定种类的辅料均可降低赤芍提取物的临界相对湿度和平衡吸湿量。[结论]提取过程的分离纯化和辅料的合理选择可以改善赤芍提取物的吸湿性,起到一定的防潮效果。[Objective] To study the moisture absorption property of Paeoniae Radix Rubra extract and to investigate the influences of different extractive process and adjuvants. [Methods] The moisture absorption percent of samples were determined with powder moisture absorption method, the moisture absorption properties of Paeoniae Radix Rubra extract and the influences of different extraction process and adjuvant were evaluated by initial moisture absorption speed, moisture absorption accelerated speed, equilibrium moisture absorption time, equilibrium moisture content and the Critical relative humidity. [Results] The equilibrium moisture content and the critical relative humidity were both decreased after macroporous resin-adsorption process and different kinds of adjuvant. [Conclusion] A proper separation and purification on extractive process or rational use of excipients can improve the moisture absorption properties of Paeoniae Radix Rubra extract and avoid from wetness.

关 键 词：赤芍提取物 大孔吸附树脂 辅料 平衡吸湿量 临界相对湿度 

分 类 号：R283[医药卫生—中药学]