抵当汤加减治疗糖尿病肾病微量蛋白尿的回顾性分析  

Retrospective analysis on modified Didang Tang for treating microalbuminuria of diabetic nephropathy

作　　者：田佳星[1,2] 赵林华[1] 周强[1] 仝小林[1] 

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]北京中医药大学

出　　处：《北京中医药大学学报（中医临床版）》2012年第6期7-10,共4页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家科技部中医药行业科研专项(No.201007004)

摘　　要：目的观察抵当汤加减治疗糖尿病肾病微量蛋白尿的临床疗效。方法采用回顾性分析研究方法,采集我院内分泌科仝小林教授门诊病例中符合入选标准的糖尿病肾病患者,经中医辨治服用汤药,观察服用汤药前后尿微量白蛋白排泄率(UAER)、糖化血红蛋白(HbA1c)、血压、血脂的变化,运用统计学方法进行数据处理分析。结果治疗3,6个月后,UAER较治疗前显著降低(P<0.01),总有效率分别为92.1%和90.5%;治疗3个月后HbA1c、收缩压(SBP)、总胆固醇(TC)降低有统计学意义(P<0.05,P<0.01),其他指标改善无统计学差异。结论抵当汤加减可改善糖尿病肾病患者微量蛋白尿,并对降低HbA1c、SBP、TC具有一定的疗效。Objective To observe the curative effect of modified Didang Tang on microalbuminuria of diabetic nephropathy （DN）. Methods The method of retrospective analysis was applied to collect the eligible DN patients from the outpatients treated by Professor TONG Xiao-lin in the Department of Endocrinology of our hospital. All patients were given decoction after syndrome differentiation. The changes of urinary albumin excretion rate （UAER）, HbA 1 C, blood pressure and blood fat were observed before and after the treatment. The statistic method was used to process and analyze the data. Results after 3 and 6 months, UAER decreased significantly （P〈0.01） and the total effective rate was, respectively, 92.1% and 90.5%. After 3 months the increase of HbA1C, systolic pressure and total cholesterol had statistical significance （P〈0.05, P〈0.01）. The changes of other indexes had no statistical differences. Conclusion Modified Didang Tang can ameliorate microalbuminuria and reduce HbA1C, systolic pressure and total cholesterol in DN patients.

关 键 词：糖尿病肾病 尿微量白蛋白 抵当汤 

分 类 号：R256.5[医药卫生—中医内科学]