糖尿病肾病患者胎孕期岁运特点以及相关危险因素的临床研究  

Characteristics of circuit of year in prenatal period and related risk factors in patients with diabetic nephropathy

作　　者：叶正华[1] 柳红芳[1] 刘变玲[1] 

机构地区：[1]北京中医药大学东直门医院内分泌科,中医内科学教育部重点实验室,北京市普通高校重点实验室,北京100700

出　　处：《北京中医药大学学报（中医临床版）》2012年第6期10-12,共3页Journal of Beijing University of Traditional Chinese Medicine

基　　金：首都特色基金项目(No.Z111107058811058);国家自然科学基金项目(No.81072735);北京市科委重大项目(No.Z111107056811043);国家财政部中药新药临床评价研究技术平台基金项目(No.2011ZX09302)

摘　　要：目的探讨糖尿病肾病患者胎孕期岁运与其发病的相关性,以及与糖尿病肾病相关的危险因素。方法共收集436例东直门医院肾内科住院糖尿病患者的出生日期的岁运信息以及合并症情况、一般人口学资料等,分成糖尿病肾病组共277例,非糖尿病肾病组159例,分组进行比较。结果合并高血压、冠心病、血脂异常,老年人(年龄≥60岁)是并发糖尿病肾病的危险因素,在各个合并症中,他们的构成比差异存在显著性(P<0.05)。可能引起糖尿病肾病患病率增加的岁运是土运不足。结论糖尿病肾病的相关危险因素有合并高血压、冠心病、血脂异常、年龄≥60岁,岁运当中的土运不足。糖尿病肾病发病与其胎孕期岁运有一定的相关性。Objective To investigate the relationship between the circuit of year in prenatal period and morbidity of diabetic nephropathy （DN）a nd related risk factors in DN patients. Methods The information about circuit of year in their birth dates, complications and general demographic data were colleted from 436 patients with diabetes hospitalized in the Department of Nephrology of Dongzhimen Hospital. All patients were divided into DN group （n= 277） and non-DN group （n=159） and given comparison. Results The risk factors of DN included hypertension, coronary heart disease （CHD）, dyslipidemia and oldness （over 60） and the difference in their constituent ratio among all complication had significance （P〈0.05）. The circuit of year inducing possibly the increase of DN morbidity was the deficiency of Tu circuit. Conclusion The related risk factors of DN include hypertension, CHD, dyslipidemia and oldness （over 60）, and the deficiency of Tu circuit. The morbidity of DN is correlated to the circuit of year in prenatal period.

关 键 词：糖尿病肾病 岁运 相关性 危险因素 

分 类 号：R256.5[医药卫生—中医内科学]