三七花总皂苷降压作用研究  

Effect Study on Blood Pressure by Panax Notoginseng Flower Saponins

作　　者：曹敏[1] 王佑华[1] 王福波[2] 周端[1] 周莉[1] 梁逸强[1] 童存存[1] 方邦江[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海200032 [2]上海中医药大学,上海200032

出　　处：《光明中医》2012年第7期1314-1315,共2页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：上海市高新技术产业科技开发基金项目(NO.沪创新J-58)

摘　　要：目的观察三七花总皂苷对自发性高血压大鼠(SHR)血压、心率的影响作用时间特点。方法以SHR为研究对象,ACL-NIBP鼠尾无创血压测量分析系统,记录30分钟、60分钟、90分钟、120分钟、180分钟、240分钟分别监测大鼠尾动脉收缩压、舒张压、心率。结果三七花总皂苷30分钟左右出现降压效果,90～180分钟达高峰,240分钟血压开始出现回升,对心率无影响。结论三七花总皂苷具有降低血压作用。Objective To study the influence of Panax Notoginseng Flower Saponins(PNFS) on blood pressure and heart rate of spontaneous hypertension rats(SHR) during different time.Methods Blood pressure and heart rate of the rats were recorded respectively by power1ab system after treatment to PNFS at 30 minutes,60 minutes,90 minutes,120 minutes,180 minutes,240 minutes.Results Systolic pressure and diastolic pressure were declined after 30 minutes,and it will last 4 hours,while the heart rate had no significant change.Conclusion PNFS could 1ower blood pressure in spo ntaneous hypertension rats effectively.

关 键 词：三七花总皂苷 自发性高血压 

分 类 号：R285.5[医药卫生—中药学]