2006～2010年石河子市无偿献血者血液检测阳性模式调查分析  

Investigation and study on ALT positive model in blood donors in Shihezi city between 2006 and 2010

作　　者：王桂萍[1] 张丽翠[2] 程江[2] 

机构地区：[1]新疆维吾尔自治区石河子市中心血站,832000 [2]石河子大学医学院第一附属医院检验科,新疆832002

出　　处：《检验医学与临床》2012年第24期3056-3057,共2页Laboratory Medicine and Clinic

摘　　要：目的调查石河子市无偿献血者中血液指标丙氨酸氨基转移酶(ALT)、乙型肝炎病毒表面抗原(HB-sAg)、丙型肝炎病毒抗体(抗-HCV)、梅毒螺旋体抗体(抗-TP)阳性模式的种类与分布,探讨ALT与HBsAg、抗-HCV、抗-TP阳性模式彼此的相关程度,试图寻找有效的筛检模式,为筛检献血者提供理论数据支持,保证血液安全。方法调查2006～2010年46 999例石河子市无偿献血者血液检测指标数据,对ALT阳性模式进行统计分析。结果 2006～2010年46 999例石河子市无偿献血者总阳性人数为2 558例,其中ALT阳性1 475例,HBsAg阳性511例,抗-HCV阳性406例,抗-TP阳性166例。在ALT阳性模式中,ALT单项阳性率94.85%,ALT与HBsAg双项阳性率2.57%,ALT与抗-HCV双项阳性率1.41%;在HBsAg阳性模式中,HBsAg单项阳性率90.28%;在抗-HCV阳性模式中,抗-HCV单项阳性率89.82%。结论 ALT与HBsAg关联程度强于ALT与抗-HCV,建议加强献血前的ALT与HBsAg的筛检,以有效降低复检阳性率。Objective To investigate the ALT,HBsAg,anti-HCV and anti-TP positive model types in Shihezi city,and to study the correlations of ALT with HBsAg,anti-HCV and anti-TP as seeking for an effective screening model to have theoretical data support for blood donor selection in order to have a better guarantee for blood using safety. Methods 46 999 blood donors＇ data of blood indexes and analysis of ALT -positive mode in Shihezi region were investigated from 2006 to 2010. Results The total positive number of 46999 blood donors was 2 558,of which ALT, HBsAg,anti- HCV,and anti-TP positive cases were 1 475,511,406 and 166. In ALT positive model,the ALT single positive rate was 94.85% ,ALT and HBsAg double positive rate was 2.57% ,ALT and anti- HCV double positive rate wasl. 41%. In HBsAg positive model, HBsAg single positive rate was 90.28 %. In anti- HCV positive model,anti- HCV single positive rate was 89.82%. Conclusion The correlation level between ALT and HBsAg is better than that between ALT and anti-HCV. Therefore, blood detections of ALT and HBsAg are still important. Quick screening before blood donation can effectively decrease the positive rate in re-detection.

关 键 词：献血者 阳性模式 筛检模式 血液安全性 

分 类 号：R193.3[医药卫生—卫生事业管理]