肺栓塞与D-二聚体相关性及影响因素  

Correlative analysis of D-dimer for the inpatients with pulmonary embolism

作　　者：曹艳霞[1] 吴颂红[1] 王彬生[1] 苏剑[1] 石宁[1] 李晓东[1] 

机构地区：[1]河北大学附属医院核医学科,河北保定071000

出　　处：《医学研究与教育》2012年第6期10-12,24,共4页Medical Research and Education

基　　金：河北大学校基金资助项目(2007Y14)

摘　　要：目的探讨肺栓塞患者D-二聚体水平变化,研究其影响因素。方法回顾性调查分析379例肺栓塞患者的临床资料,分析肺栓塞与D-二聚体阳性率与采血时间及是否应用溶栓药物之间的关系。结果 24 h内未应用溶栓药物组的阳性率(98.20%)明显高于应用溶栓药物组(78.31%),P<0.05。未应用溶栓药患者,发病24 h内采血,D-二聚体阳性率(98.20%)明显高于24 h后采血组(85.14%),P<0.05。结论肺栓塞患者D-二聚体水平与样本的留取时间及留取样本前有无应用溶栓药密切相关。Objective To study the D-dimer levels of the patients with pulmonary embolism and analyze its influencing factors.Methods One hundred and eighty patients with pulmonary embolism from 2005 to 2009 were reviewed retrospectively,and the relation among pulmonary embolism and D-dimer were analyzed.Results The positive rate（78.31%） of the samples that used the drug was lower than the positive rate（98.20%） of the samples that had not used the drug.The positive rate（85.14%） of the samples that collected the blood after 24 hours was lower than the positive rate（98.20%） of the samples that collected the blood in 24 hours.Conclusion The results show that the positive rate of the D-dimer is related to the time and drug-use before the samples of obtaining.

关 键 词：肺栓塞 D-二聚体 影响因素 

分 类 号：R817.4[医药卫生—影像医学与核医学]