120例患者使用β-内酰胺类抗生素交叉过敏反应相关性的研究  

The Class Antibiotic Cross Allergic Reaction Correlation Studies of 120 Cases of Patients Who Use Beta-lactamase-producing

作　　者：张洁[1] 欧阳爱军[1] 王鹏[1] 

机构地区：[1]南昌大学第一附属医院,江西南昌330006

出　　处：《中国医药指南》2012年第34期36-39,共4页Guide of China Medicine

摘　　要：目的通过对各类β-内酰胺类药物相互交叉过敏反应相关性研究,找寻各类β-内酰胺类药物相互交叉过敏反应比率。为临床合理选择β-内酰胺类药物提供理论依据。方法通过对在2011年3月至5月期间住院的有β-内酰胺类抗生素过敏患者进行调查,对结果进行回顾性统计分析。结果青霉素与头孢类抗生素发生交叉过敏的的概率较低;头孢类抗生素与其他β-内酰胺类药物相互交叉过敏反应的概率相对较高。结论对于有青霉素过敏的患者且头孢皮试阴性的患者,使用头孢类抗生素是安全的。Objective Though the correlation studies of all kinds of beta beta-lactamase-producing drugs overlapping allergic reaction,to find all kinds of beta beta-lactamase-producing drugs overlapping allergic reaction ratio.For clinical rational choice beta beta-lactamase-producing provide theoretical basis of drugs.Methods Based on the march in 2011 to five months in the hospital there are beta beta-lactamase-producing class antibiotic allergy patients to survey,statistics and analysis results.Results With cephalosporin antibiotic penicillin allergies to the probability of happened cross low;Cephalosporin antibiotic and other beta beta-lactamase-producing drugs overlapping the probability of an allergic reaction are relatively high.Conclusion Patients with penicillin allergies and skin test negatie patient cephalosporins,use cephalosporin antibiotic is safe.

关 键 词：Β-内酰胺类抗生素 交叉过敏 研究 

分 类 号：R978.1[医药卫生—药品]