生殖道支原体感染情况及耐药性分析  

Detection and the Drug Resistance Analysis of Mycoplasma with Urogenital Tract Infections

作　　者：王海滨[1] 石新慧[1] 朱静[1] 于勇[1] 

机构地区：[1]解放军总医院第一附属医院检验科,北京100048

出　　处：《中国医刊》2012年第12期38-39,共2页Chinese Journal of Medicine

摘　　要：目的分析生殖道支原体感染类型的分布及耐药情况,为临床合理用药提供科学依据。方法收集1536例妇产科门诊及住院女性患者,采用支原体培养鉴定、药敏试剂盒,检测支原体感染类型的分布及耐药情况。结果生殖道支原体感染检测总阳性率76.82%,其中单纯解脲脲原体(Uu)感染型构成比为35.85%,单纯人型支原体(Mh)感染型构成比为7.29%,而Uu+Mh混合感染型构成比为56.86%。耐药性分析发现,对于各种支原体感染类型,交沙霉素、美满霉素和强力霉素的敏感度较高,而甲砜霉素、克林霉素、红霉素、罗红霉素、克拉霉素和阿奇霉素的耐药程度较高。结论本研究结果对了解该支原体感染的分布情况以及抗菌药物敏感性筛选具有一定的指导意义。Objective To provide the useful clues for clinical treatment, we investigated the infection and the drug resistance condition of mycoplasma in patients with urogenital tract infections. Methods We analyzed the distribu- tion of mycoplasma infection and conducted the susceptibility test with the urethra secretion of 1536 patients by using the commercial kits. Results The positive rate of mycoplasma infection was 76.82% among the 1536 subjects. Sim- ple Uu and Mh infection rates were 35.85% and 7.29%, respectively. The mixture infection rate of Uu and Mh was 56.86%. The highest susceptibility was observed in Josamycin. In contrast, the Thiamphenicol, Clindamycin, and Erythromycin had the high resistance rates. Conclusion The results revealed the mycoplasma distribution in pa- tients with urogenital tract infections, which would provide useful clues for the clinical treatments.

关 键 词：生殖道支原体感染 解脲脲原体 人型支原体 药敏试验 

分 类 号：R518.9[医药卫生—内科学]