大连地区感染性腹泻病原监测结果分析  

Pathogenic surveillance and analysis on infectious diarrhea in Dalian

作　　者：徐明玉[1] 任月[1] 韩焱[1] 

机构地区：[1]大连市疾病预防控制中心,辽宁大连116000

出　　处：《中国微生态学杂志》2012年第12期1108-1109,1114,共3页Chinese Journal of Microecology

摘　　要：目的了解大连地区感染性腹泻病原菌的种类和流行特征,为感染性腹泻的预防控制和临床治疗提供依据。方法采用常规粪便培养方法,对分离菌做血清学分型,用MicroScan WalkAway-40全自动细菌鉴定及药敏分析仪对分离菌做生化鉴定,对检出的志贺菌做药敏试验,并用WHONET 5.4软件对药敏结果进行统计分析。结果监测872例腹泻患者样本,检出感染性腹泻病原菌109株,阳性率为12.5%,其中志贺菌所占比例最大,其次为沙门菌,副溶血弧菌排第三。志贺菌对碳青霉烯类、氟喹诺酮类和头孢菌素类等敏感,对青霉素类和复方磺胺类耐药。结论志贺菌是大连地区感染性腹泻的首要病原菌,沙门菌和副溶血弧菌次之,应依据此监测结果做好大连地区腹泻病的防治工作;同时根据耐药性监测结果合理使用抗生素应对志贺菌,减少耐药菌株出现。Objective To understand the epidemic characteristics and types of infectious diarrhea pathogens in Dalian,and provide references for the prevention and control as well as clinical treatment of infectious diarrhea.Methods The pathogen strains were isolated by routine stool culture and the serological typing was performed.The biochemical identification of the isolates and drug susceptibility test of Shigella were carried out by Automated Microbiology Analyzer MicroScan WalkAway-40.The data were analyzed by WHONET 5.4 software.Results 109 intestinal pathogenic bacteria were detected out of 872 samples（12.5%）,in which Shigella accounted for the largest proportion,followed by Salmonella and Parahaemolyticus.The Shigella strains were sensitive to Carbapenems,Fluoroquinolones,Cephalosporins,while resistant to Penicillins and Sulfonamides.Conclusion Shigella is the primary pathogen causing infectious diarrhea in Dalian,followed by Salmonella and Parahaemolyticus.The prevention and control of diarrheal disease in Dalian should be based on the surveillance results,and antibiotics ought to be used according to the results of drug resistance test so as to reduce the emergence of Shigella resistant strains.

关 键 词：感染性腹泻 病原菌 监测 药敏试验 

分 类 号：R378[医药卫生—病原生物学]