466例成年女性宫颈支原体感染现状及药敏分析  

466 cases of adult female cervical mycoplasma infection status and analysis of drug susceptibility

作　　者：曾旭云 

机构地区：[1]成都市金牛区人民医院检验科,四川成都610036

出　　处：《四川生理科学杂志》2012年第4期158-160,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:为了解本地区成年女性子宫颈解脲支原体(Uu)及人型支原体(Mh)的分布及抗生素的药敏现状,为临床诊断和合理用药提供依据。方法:应用支原体培养、鉴定、药敏一体化试剂盒,对919例疑为支原体感染患者的宫颈分泌物进行培养、鉴定与分型,并测定其对10种常用抗生素的敏感性。结果:919例可疑病例中支原体培养阳性466例(50.7%),其中单纯解脲支原体(Uu)阳性395例(43.0%),单纯人型支原体(Mh)阳性20例(2.2%),Uu+Mh阳性混合感染51例(5.5%);药敏结果显示,支原体对10种抗生素敏感率排名:交沙霉素96.78%、克拉霉素93.13%、阿奇霉素92.92%,耐药率排名:司帕沙星51.29%、氧氟沙星40.99%、左氧氟沙星36.91%。结论:本地区成年妇女生殖道临床感染支原体主要为解脲支原体(Uu),交沙霉素等新一代大环内酯类抗生素为首选药物,喹诺酮类抗生素耐药率高。Objective： To understand the present situation of drug susceptibi!ity of antibiotics and distribution urine ureaplasma （Uu） and mycoplasma hominis （Mh） infection in local women and to provide proof for clinical treatment. Methods： Cervical discharge of 919 suspected women was cultured for mycop]asma and identified for classification, and tested the susceptibility of 1@ com- mon-used antibiotics. Result： 466 patients of 919 suspected cases were positive for mycoplasma culture （50.7%）; among whom 395 patients were positive for gu （accounting for 43.0%）, 20 patients positive for Mh （accounting for 2.2%）, 51 patients positive for combination of Uu and Mh （accounting for 5.5 %）. Results of susceptibility indicated that mycoplasma-susceptible antibiotics were Josamycin （96. 78%）, Clarivhromycin （93. 13%）, Acithromycin（92. 92%）, and mycopiasma-resistant antibiotics were Sparfloxacin （51.29%）, Ofloxacin （10.99%） and Levofloxacin （36. 91%）. Conclusion： The predominant mycoplasma of cervical infection for lo- cal adult women is Uu, new generation of macrolides like Josamycin is the drug of first choice while Quinolones are the most resistant antibiotics.

关 键 词：成年女性 宫颈分泌物 解脲支原体 人型支原体 药敏分析 

分 类 号：R446.5[医药卫生—诊断学]