糖尿病胃轻瘫发病机制的研究进展  

Pathogenesis of diabetic gastroparesis research progress

作　　者：孔艳华[1] 祝捷[2] 郜同心[3] 

机构地区：[1]北京中医药大学,北京100029 [2]中日友好医院内分泌代谢病中心中医糖尿病科,北京100029 [3]河北医科大学,河北石家庄050017

出　　处：《中国医药导报》2012年第33期25-26,共2页China Medical Herald

基　　金：中日友好医院院级科研课题(课题名称:滋阴降胃汤治疗糖尿病胃轻瘫的临床观察;课题编号:2010-QN-23)

摘　　要：糖尿病性胃轻瘫(diabetic gastroparesis,DGP),是糖尿病的慢性并发症之一,其主要特点是在没有机械性梗阻的情况下出现胃排空延迟,包括胃排空的极度延缓与胃排空延迟有关的胃动力障碍。其典型症状为腹胀、早饱、厌食、嗳气、恶心、呕吐、体重减轻,通常在餐后较为严重。体格检查可见胃区胀满,可闻及震水音。X线检查显示胃蠕动减慢、减弱,胃扩张或弛缓,排空延迟,幽门开放等征象。胃镜检查可见胃体或胃窦部黏膜充血、水肿、糜烂。胃电图检查有胃蠕动功能减弱。目前DGP的发病机制尚未明确,本文就DGP的发病机制的最新研究进展作一综述。Diabetic gastroparesis（DGP） is one of the complications of diabetes,which is characterized by delayed gastric empty in the absence of mechanical obstruction.Its typical symptoms include abdominal distension,early enough,anorexia,gas,nausea,vomiting,loss of weight,symptoms are get seriously usually after a meal.Physical examination shows stomach fullness,succussion splash.X-ray examination reveals a slower gastric peristalsis,gastric dilatation or relaxtion,delayed gastric emptying,pyloric opening and other signs.Gastroscopy shows a series of stomach or gastric antrum mucosa,such as hyperemia,edema,erosion.Electrogastrogram shows gastric peristalsis function weakened.At present,the pathogenesis of DGP has not been clearly clarified,the pathogenesis of DGP of the latest research progress are summarized in this review.

关 键 词：糖尿病胃轻瘫 发病机制 研究进展 

分 类 号：R587.1[医药卫生—内分泌]