人参补肺丸对慢性阻塞性肺疾病稳定期患者肺功能和生活质量影响的临床研究  

Clinical Research of Renshen Bufei Pill on Lung Function and Quality of Life of COPD Patients in Stable Period

作　　者：贾小江[1] 黄超群[1] 

机构地区：[1]遂宁市中医院,四川遂宁629000

出　　处：《四川中医》2012年第11期67-69,共3页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:研究人参补肺丸对慢性阻塞性肺疾病(COPD)稳定期患者肺功能及生活质量的影响。方法:将120例COPD患者随机分为2组,治疗组60例给予人参补肺丸联合舒利迭治疗,对照组60例仅给予舒利迭吸入,连续治疗12周。治疗后比较两组肺功能指标变化情况、生活质量(QOL)评定,并记录症状、体征评分。结果:中西药结合组总有效率96.66%,西药对照组总有效率68.33%,差异有显著性意义(P<0.05)。中西药结合组治疗后肺通气功能各项指标比治疗前明显改善(P<0.05);对照组FEV1治疗后较治疗前有明显改善(P<0.05);中西药结合组治疗后QOL总均分、日常生活能力、社会活动能力、抑郁症状和焦虑症状评分显著增加(P<0.01)。结论:人参补肺丸能改善慢性阻塞性肺疾病稳定期患者的临床症状,延缓肺功能下降速度,显著改善患者的生活质量。Objective： To study the influence of Renshen Bufei Pill on lung function and life quality of chronic obstructive pulmonary disease （COPD） patients in stable period. Methods： 120cases of COPD patients were randomly divided into 2groups. In treatment group, 60patients were given the Renshen Bufei Pill and Seretide, while in control group, 60patients were treated with Seretide inhalation. The treatment course was 12weeks. After the treatment, changes in lung function indicators and quality of life （QOL） assessment were compared between two groups, and symptoms and signs score would be recorded. Results： Com- pared with treatment group （96. 66% ） , the total effective rate of control group was 68. 33% , the difference was significant （P 〈0. 05）. The improvement of pulmonary function indicators in treatment group after treatment was significant （P〈O. 05）. The improvement of FEV1 in control group was significant （P〈0. 05）. The treatment group showed obvious increase after treatment in aspects of QOL total average score, daily living skills, social skills, depression and anxiety symptoms score （ P〈0. 01 ）. Con- clusion： Renshen Bufei Pill is effective at improving clinical symptoms of COPD patients in stable period, slowing the decline of lung function, and significantly improving quality of life.

关 键 词：COPD 稳定期 人参补肺丸 肺功能 生活质量 

分 类 号：R563.3[医药卫生—呼吸系统]