换血对新生儿血糖及酸碱平衡的影响  

Effect of exchange transfusion on blood glucose and acid-base balance in neonates

作　　者：李清平[1] 董文斌[1] 翟雪松[1] 王胜会[1] 

机构地区：[1]泸州医学院附属医院新生儿科,四川泸州646000

出　　处：《临床儿科杂志》2012年第12期1168-1171,共4页Journal of Clinical Pediatrics

摘　　要：目的探讨换血对新生儿血糖及酸碱平衡的影响。方法将137例新生儿分为4组,采用不同红细胞(RBC)与血浆的比例行外周动静脉同步换血,并检测配制好的血液标本和换血前后新生儿的电解质和血糖、血气分析指标及换血前后新生儿的血清总胆红素。结果总的胆红素换出率为(54.36±10.29)%;换血后发生高血糖者126例,血糖由(4.61±1.89)mmol/L上升到(11.38±3.66)mmol/L,差异有统计学意义(t=20.76,P<0.01)。换血前HCO3-(18.42±3.85)mol/L,换血后血清HCO3-(15.21±3.55)mol/L,差异有统计学意义(t=9.42,P<0.01)。结论新生儿换血会导致暂时性的血糖升高和一定程度的HCO3-下降。Objective To investigate the effect of exchange transfusion on blood glucose and acid-base balance in new borns. Methods One hundred and thirty-seven newborns were divided into four groups. Synchronous peripheral arteriovenous exchange transfusion was performed with different ratios of red blood cells （RBC） and blood plasma. Blood glucose, blood gas, electrolytes and serum total bilirubin were measured before and after blood transfusion. Results After exchange transfu sion, blood glucose was significantly increased from （4.61±1.89） mmol/L to （11.38±3.66） mmol/L （t=20.76, P〈0.01）. HCO3 con centration was significantly decreased from （18.42±3.85） mol/L to （15.21±3.55） mol/L （t=9.42,P〈0.01）. Conclusions Exchange transfusion on newborns temporarily increases the blood glucose and decreases the HCO3 concentration.

关 键 词：换血术 血糖 酸碱平衡 新生儿 

分 类 号：R722.1[医药卫生—儿科]