立体定向颅内血肿穿刺对脑出血后抑郁症发病率的影响  

Effects of stereotactic puncturing and draining therapy for intracerebral hemorrhage on incidence of post-stroke depression

作　　者：李罡[1] 苏治国[1] 赵玉军[2] 刘晓智[1] 王骏飞[1] 刘振林[1] 

机构地区：[1]天津市第五中心医院神经外科,300450 [2]天津市第五中心医院神经内科,300450

出　　处：《中华神经外科杂志》2012年第12期1215-1218,共4页Chinese Journal of Neurosurgery

基　　金：天津市滨海新区卫生局联合攻关项目（2011BHKL002）;天津市塘沽区科委科技兴区项目（2011XQ13-08）

摘　　要：目的对比传统保守治疗和立体定向颅内血肿穿刺引流术两种治疗方法下脑出血后抑郁症的发病率。方法64例脑出血患者分别采用保守治疗和立体定向颅内血肿穿刺引流术。对比病程第14天及第90天时患者NIHSS评分及HAMD评分，评价患者神经功能缺失情况及抑郁症程度。结果在病程第14天及90天，两组NIHSS得分均有下降，且差异有统计学意义（P〈0．01）；第90天时两组mRS得分有明显差异；第14天时，两组抑郁症发病人数差异无统计学意义，第90天时两组抑郁症发病人数差异有统计学意义（P〈0．05）。结论立体定向颅内血肿穿刺引流术相对传统保守治疗可缩短病程，加快神经功能恢复，改善患者预后及生存质量，并且可降低脑出血后抑郁症的发生。Objective To study the difference of incidence of post - stroke depression between stereotactic puncturing and draining therapy and medical conservative treatment. Methods The clinical data of 64 patients with intracerebral hemorrhage in our department form January 2010 to December 2011 were collected and compared. Results On the 14th day and 90th day after the onset of stroke, the values of NIHSS in two groups were both decreased. There was significant difference between the two groups. There was significant difference between the values of mRS in two groups. There was no significant difference in the incidence of depression after intracerebral hemorrhage on the 14th day after onset between two groups, but the difference of them was became significant on the 90th day after onset. Conclusions Compared with conservative therapy, stereotactic puncturing and draining therapy could promote the recovery of neurological function rapidly, improve the outcome and quality of life, reduce the incidence of depression after intracerebral hemorrhage.

关 键 词：脑出血 卒中后抑郁 立体定向 保守治疗 

分 类 号：R651.1[医药卫生—外科学]