3．0TMR对梅尼埃病内耳淋巴液流速的研究  

Study of flow rate of inner ear lymph fluid in Meniere＇s disease by 3.0T MR scanner

作　　者：李茗[1] 张冰[1] 王娇[1] 周正扬[1] 陈飞[1] 俞海平[1] 朱斌[1] 李晨[1] 陈伟波 尹震宇[3] 

机构地区：[1]南京大学医学院附属鼓楼医院 放射科 [2]飞利浦医疗保健事业部 [3]南京大学医学院附属鼓楼医院 老年科,江苏南京210008

出　　处：《实用放射学杂志》2012年第12期1857-1861,共5页Journal of Practical Radiology

基　　金：南京市医学科技发展青年科技人才启动项目（QYK09167）.

摘　　要：目的 用相位对比动态MRI技术研究梅尼埃病内耳淋巴液流速。方法 使用3．0TMR扫描仪，采用相位对比动态MRI的Q-Flow方法对30例正常人及26例梅尼埃病患者的耳蜗底转角处的淋巴液流速进行测量。结果30例正常人的耳蜗底转角处平均最大流速值分别为：左耳（0．47±0．47）cm／s，右耳（0．59±0．62）cm／s；26例梅尼埃病患者的耳蜗底转角处平均最大流速值分别为：左耳（1.00±1．07）cm／s，右耳（0．70±0．62）cm／s。2组间左耳具有统计学差异（P〈0．05），右耳无统计学差异（P〉0．05）。结论 使用3．0TMR扫描仪、Q-Flow序列能检测出人体内耳淋巴液的流动，为临床诊断梅尼埃病提供了客观诊断依据。Objective To measure the flow rate of inner ear lymph in patients with Meniere＇s by using phase contrast dynamicsprotocol on 3.0T MR scanner. Methods Thirty normal subjects and 26 clinical patients with Meniere＇ s disease were scanned to measure the lymph flow rate of the cochlear corner on a 3.0T MR scanner through the method of Q Flow of phase contrast dynamic MRI. Results Thcaverage maximum flow rate of the cochlear corner of 30 normal subjects was （0.47±0.47） cm/s in left ear, and （0. 59±0. 62） cm/s in right ear, respectively. The average maximum flow rate value of 26 patients was （1.00±1.07） cm/s in left ear, and （0.70± 0.62） cm/s in right ear, respectively. There was significant difference between the average maximum flow rate val ue of left ears between the two groups （P〈0.05）. But there was no significant difference between that of right ears （P〉0.05）. Conclusion The Q-Flow sequence of 3.0T MR scanner can measure the flow rate of the human inner ear lymph fluid.

关 键 词：梅尼埃病 内耳淋巴液 相位对比法 磁共振成像 

分 类 号：R764.3[医药卫生—耳鼻咽喉科] R445.2[医药卫生—临床医学]