代谢综合征与冠状动脉狭窄程度及心血管危险评分的关系  

Relation Between Metabolic Syndrome and Coronary Artery Stenosis,Cardiovascular Risk Score

作　　者：李婉[1] 白小涓[1] 

机构地区：[1]中国医科大学附属第一医院老年病科,辽宁省沈阳市110001

出　　处：《中国动脉硬化杂志》2012年第12期1133-1136,共4页Chinese Journal of Arteriosclerosis

摘　　要：目的了解代谢综合征患者冠状动脉狭窄程度及心血管危险评分的特点,以探讨代谢综合征与后两者之间的关系。方法连续收集胸部不适并行冠状动脉CT检查的136例患者,所有患者均检查血压、空腹血糖及血脂,包括甘油三酯、总胆固醇、高密度脂蛋白胆固醇及低密度脂蛋白胆固醇。应用美国2001年NCEP-ATPⅢ代谢综合征诊断标准,将其分为代谢综合征组及非代谢综合征组。冠状动脉狭窄程度用多层螺旋CT测量,比较两组间冠状动脉狭窄程度的差异,并对心血管危险评分中各项指标的差异进行比较。结果冠状动脉狭窄程度代谢综合征组均较非代谢综合征组为重,两组的高血压、糖尿病患者、血脂异常及心血管危险评分存在明显差异。结论代谢综合征患者冠状动脉狭窄程度较重,且多数心血管危险评分较高。代谢综合征可作为冠心病的重要危险因素,早期全面干预其中的各个成分有助于冠心病的防治。Aim To analyze the characteristics of coronary artery stenosis and the cardiovascular risk score i. e. Framingham risk score （FRS） in the metabolic syndrome （MS） patients. Methods Collect 136 patients who have chest discomfort and have undergone coronary multi slicespiral CT examination continuously, and check their blood pres- sure, fasting blood glucose and lipids, including triglycerides, total cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol. Use the United States 2001 NCEP-ATP Ⅲ diagnostic criteria of metabolic syndrome to di- vide the study population into non-MS group and MS group. Use multi-slicespiral CT to measure the degree of coronary ar- tery stenosis, and compare the differences of the coronary artery stenosis between non-MS group and MS group, and also compare the differences of the contents in the cardiovascular risk score. Results MS group shows more severe coro- R nary artery stenosis compared with non-MS group, and the patients of hypertension and diabetes, dyslipidemia and cardio- vascular risk score shows significant difference. Conclusions Metabolic syndrome suffered more severe coronary arter- y stenosis, and most of them have higher cardiovascular risk score. MS can be used as an important risk factor of coronary heart disease, and interventing the elements of MS early could contribute to the prevention and treatment of coronary heart disease.

关 键 词：代谢综合征 冠状动脉 多层螺旋CT FRS评分 

分 类 号：R5[医药卫生—内科学]