河套大黄的蒽醌类成分研究  

Studies on the Anthraquinones of Hotao Rhubarb (Pheum hotaoense)

作　　者：李军林[1] 王爱芹[1] 李家实[2] 贺文义[3] 孔漫[3] 

机构地区：[1]军事医学科学院放射医学研究所,北京100850 [2]北京中医药大学中药学院 [3]中国医学科学院中国协和医科大学药物研究所

出　　处：《中草药》2000年第5期321-324,共4页Chinese Traditional and Herbal Drugs

摘　　要：从河套大黄干燥根与根茎的甲醇提取物中分得 10个蒽醌类成分。经化学方法和波谱学鉴定 ,确定它们的结构分别为 :大黄酚 (chrysophanol, )、大黄素甲醚 (physcion, )、大黄素 (emodin, )、芦荟大黄素 (aloe-emodin, )、大黄酸 (rhein, )、大黄酚 - 1和 8- O- β- D-吡喃葡萄糖苷 (chrysophanol- 1and 8- O- β- D-glucopyranoside, a和 b)、大黄酚 - 8- O-β- D- (6′- O-没食子酰 ) -吡喃葡萄糖苷〔chrysophanol- 8- O-β- D- (6′- O-galloyl) - glucopyranoside, 〕、大黄素甲醚 - 8- O- β- D-吡喃葡萄糖苷 (physcion- 8- O- β- D- glucopyranoside, )、芦荟大黄素 - 8- O- β- D-吡喃葡萄糖苷 (aloe- emodin- 8- O- β- D- glucopyranoside, )。其中 为一新化合物 , 、 、 系首次从该植物中分得。From the methanolic extract of root and stem of Rheum hotaoense C. Y. Cheng et C. T. Kao. ten anthraquinones were isolated. Their structures were identified by chemical and spectroscopic methods as chrysophanol (Ⅰ), physcion (Ⅱ), emodin (Ⅲ), aloe emodin (Ⅳ), rhein (Ⅴ), chrysophanol l and 8 O β D glucopyranoside (Ⅵ a and Ⅵ b), chrysophanol 8 O β D (6′ O galloyl) glucopyranoside (Ⅶ), physcion 8 O β D glucopyranoside (Ⅷ), aloe emodin 8 O β D glucopyranoside (Ⅸ). Among which Ⅵ, Ⅷ, Ⅸ were obtained from this plant for the first time and Ⅶ is a new compound.

关 键 词：河套大黄 蒽醌 大黄酚 没食子酰 吡喃葡萄糖苷 

分 类 号：R284.1[医药卫生—中药学]