临床分离非发酵菌的耐药性分析  

Analysis on drug resistance of non-fermentative bacteria isolated from clinic

作　　者：包东武[1] 李建华[1] 

机构地区：[1]河南南阳医学高等专科学校微生物室,南阳473000

出　　处：《现代预防医学》2013年第1期134-135,共2页Modern Preventive Medicine

摘　　要：目的通过对某院临床分离非发酵菌对常用抗菌药物的耐药性分析，为临床选择抗菌药物提供依据。方法用VITEK32型全自动细菌分析系统对该院2008年1月～2010年12月临床分离的550株非发酵革兰阴性杆菌进行鉴定，药敏试验采用K—B纸片扩散法，判断标准按NCCLS2007年版进行。结果该院非发酵菌中分离率较高的为铜绿假单胞菌、鲍曼不动杆菌和嗜麦芽窄食单胞菌，分别占非发酵菌的38．9％、33．1％和16．4％。非发酵菌对头孢哌酮／舒巴坦的耐药率最低，耐药率为8．9％～15．0％。结论非发酵菌引起的感染日益增多，其耐药性也在不断增高，应引起临床医师的高度重视。OBJECTIVE To analyse the drug resistance of non-fermentative bacteria to commonly used antibiotics in clinic, and provide bases for choice of antimicrobial agents in clinic. METHODS VITEK32 type automatic bacterial analysis system was adopted in our hospital from January 2008 to December 2010, 550 clinical isolates of non-fermentative gram-negative bacilli were identified, drug sensitivity test with K-B disk diffusion method, judgment standard according to the NCCLS2007 version. RESULTS In our hospital, higher isolated rates of non-fermentation bacteria were pseudomonas aeruginosa, bauman acinetobacter and stenotrophomonas maltophilia, accounting for 38.9%, 33.1% and 16.4%. The resistance rates of non- fermentative bacteria to cefoperazone/sulbaetam were lowest, which was 8.9%-15%. CONCLUSION Infection caused by non- fermentation bacteria is increasing, its resistance also is ceaselessly heighten, which should be highly emphasized by clinicians.

关 键 词：非发酵菌 抗菌药物 耐药率 

分 类 号：R378[医药卫生—病原生物学]