妊娠兔骨折愈合的影像学研究  

Image analysis on fracture healing of pregnant rabbits

作　　者：李曙光[1] 苏英杰[1] 王志文[2] 袁强[1] 张爱国[1] 张国志[1] 李建岷[1] 

机构地区：[1]河北联合大学附属医院普外科.河北唐山063000 [2]河北联合大学中医学院

出　　处：《现代预防医学》2013年第1期136-138,145,共4页Modern Preventive Medicine

摘　　要：目的探讨妊娠对兔骨折愈合的影响。方法日本大耳白雌兔随机分成对照组、妊娠组,对照组不做处理,妊娠组交配受孕,妊娠组孕后9d分组造模成左小腿中段闭合骨折模型,按造模前、造模后即时、造模后1、2、3周各时点抽取耳缘静脉血或心穿血,提取血清后-80℃冻存。按时点计算机数字化X线成像(Computed radiography,CR)、骨密度检查,其数据行统计学检验。结果妊娠组造模后1、2、3周骨痂骨密度值[(0.456±0.019)、(0.469±0.016)、0.461±0.022)g/cm2]、骨痂骨矿质含量值[(0.773±0.103)、(0.968±0.140)、(1.127±0.213)g]均高于对照组[(0.347±0.039)、(0.372±0.039)、(0.409±0.021)g/cm2]、;(0.617±0.083)、(0.783±0.062)、(0.998±0.087)g](P﹤0.05);CR定量测得的骨痂平均光密度值,妊娠组造模后1、2、3周均高于对照组(P﹤0.05)。结论兔早中期妊娠可能对骨折愈合有促进作用。OBJECTIVE To research fracture healing of pregnant rabbits. METHODS Japanese big ears white female rabbits randomly were divided into control group and pregnancy group, pregnancy group which mating and becoming pregnant.After making model, according to 0a, 0b, 1, 2, 3 weeks, extracted blood, its serum was freeze-stored -80℃. Every rabbit of control group and pregnancy group was inspected for fracture bone CR and density, its data were analyzed. RESULTS Callus BMD IN 1, 2, 3 week was [ （0.456 ± 0.019）, （0.469 ± 0.016）, （0.461 ± 0.022） g/cm±] respectively; Callus mineral was [ （0.773 ± 0.103）, （0.968 ± 0.140）, （ 1.127 ± 0.213） g l. The two indices above were hith higher than the control group [（0.347 ± 0.039）, （0.372 ± 0.039）, （0.409 ± 0.021） g/era2] for BMD, （0.617 ± 0.083）, （0.783 ± 0.062）, （0.998 ± 0.087） g ] for mineral （P〈 0.05） ; average opticals of callus by CR determination in 1, 2, 3 weeks were higher in pregnancy group （P 〈 0.05 ）. CONCLUSION Rabbits＇ pregnancy in early metaphase promotes fracture healing.

关 键 词：骨折愈合 兔 妊娠 影像学 影响 

分 类 号：R445[医药卫生—影像医学与核医学]