畸变产物耳声发射用于耳神经外科手术中听觉监测的实验研究  

Experimental study on distortion product otoacoustic emission used for hearing monitoring in the oto-neurosurgery operation

作　　者：朱明[1] 吴皓 孙钢[1] 姜庆军[1] 李杰[1] 郁冰冰[1] 李海军[1] 

机构地区：[1]济南军区总医院医学影像科,济南250031 [2]上海市新华医院耳鼻咽喉头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2013年第1期34-36,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨畸变产物耳声发射(DPOAE)用于耳神经外科手术中听觉监测的可行性。方法:将24只纯种新西兰大白兔随机等分为3组,分别观察无手术、暴露桥脑小脑角后下压小脑、暴露面听神经复合体后阻断内听动脉血流5min共3种状态下的DPOAE值,并行组织学检查。结果:下压小脑、阻断内听动脉血流后均记录到DPOAE发生改变,部分频率未引出,引出频率的DPOAE值降低,与术前比较差异有统计学意义(P<0.05),并与组织学变化相符。结论:DPOAE能有效监控耳神经外科手术中的听损伤,具有较好的临床应用前景。Objective：To explore the feasihility of distortion product otoacoustic emission （DPOAE） used for hearing monitoring in the oto-neurosurgery operation. Method： Twenty-four rabbits were equally divided into 3 groups ：none operation（group A, n= 8） ;pressing the cerebella after the ecrebellopontion angle was exposed（group B, n=8）;Blood flow of internal auditory artery were occlusion for 5 min after the facial-acoustic nerve complex was pressed（group C, n= 8）. DPOAE value and histologic were observed. Result：In the state of pressing the care- bella and blood flow of inner hearing artery were occlusion, DPOAE amplitude values changed, part of the frequen- cies could not be indueed,DPOAE amplitude values of induced frequencies descend and nael significant difference （P〈0. 05） to preoperation, as well as correspond to histology changes, Conclusion： DPOAE could monitor the hearing loss effectively and would be one of ideal monitoring methods in the oto-neurosurgery operation.

关 键 词：畸变产物耳声发射 耳神经外科手术 听觉监测 

分 类 号：R764.9[医药卫生—耳鼻咽喉科]