女性甲状腺功能亢进患者的骨密度变化  

Change in bone mineral density in female patients with hyperthyroidism

作　　者：王玫[1] 任安[1] 孔艳华[1] 

机构地区：[1]安徽医科大学附属省立医院内分泌科,安徽合肥230001

出　　处：《安徽医药》2012年第12期1808-1809,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的观察病程及绝经与否对女性甲状腺功能亢进症(甲亢)患者骨密度的影响。方法采用双能X线骨密度仪测定328例女性甲亢患者腰椎及髋部骨密度,根据患者绝经与否分为绝经前和绝经后两组,再按病程长短分为短程和长程两个亚组,比较两组的测量结果。结果绝经前甲亢患者长程组L2及股骨干骨密度明显低于短程组(P<0.05)。绝经后甲亢患者长程组腰椎及髋部各测量部位骨密度较短程组亦显著降低(P<0.05)。结论女性甲亢患者的骨密度受甲亢病程及绝经与否的影响,较长的甲亢病程容易导致骨密度的下降,绝经后这种改变更为突出。Objective To investigate the effect of the course and menopause on the change of bone mineral density（BMD） in female patients with hyperthyroidism.Methods BMDs of hip and lumbar vertebrae were measured by dual-energy X-rays absorptiometry in 328 female patients.Patients were divided into two groups（premenopausal and postmenopausal）,again into two subgroups（short-course and long-course）.Results In the premenopausal hyperthyroidic patients,the BMDs of lumbar vertebrae 2 and femoral shaft with long-course group were significantly lower than those of short-course group（P0.05）.In the postmenopausal group with the long-course,each BMD measured had a lower level compared with that with short-course（P0.05）.Conclusion The course and menopause have an effect on the BMDs in female patients with hyperthyroidism.

关 键 词：甲状腺功能亢进症 骨密度 女性 双能X线骨密度测定 

分 类 号：R581.1[医药卫生—内分泌]