正交试验法优选健肝颗粒提取工艺  

To Select Extraction of Jiangan Granules by Orthogonal Test

作　　者：于海斌[1] 郑海云[1] 龚卫红[2] 

机构地区：[1]中国中医科学院中医药科技合作中心,北京100700 [2]北京中医药大学中药学院制药系,北京100102

出　　处：《中国现代中药》2012年第12期44-46,共3页Modern Chinese Medicine

摘　　要：目的:通过正交试验,优选处方的最佳提取工艺。方法:采用水提取方式,以水为溶剂进行提取,选择加水倍数、提取时间、提取次数3个因素,每个因素设计3个水平,按照正交试验L9(34)表进行试验。以总黄酮作为指标,综合考虑,选定最优提取工艺。结果:提取的最佳工艺条件为加8倍量水,提取3次,每次2h。结论:优选得到的提取工艺简单、稳定、可行。Objective： To experiment the best extraction optimization prescription. Methods： Select water as solvent extraction, multiple choice with water, extraction time and number as three factors, each of the three levels of design, in accordance with the orthogonal L9 （3^4） Table experiment , the composition of total flavonoids as a symbol selected the optimal extraction. Results： The optimum extraction conditions for 8 times the amount of water, 2 h as the extraction time and extracted three times. Conclusion： The optimized extraction process is simple, stable and feasible.

关 键 词：正交试验 总黄酮 健肝颗粒 

分 类 号：R282.71[医药卫生—中药学]