Three New Sesquiterpenoids from Agrocybe sp.  

作　　者：ZHENG Yong-biao LU Chun-hua XU Li SU Wen-jin SHEN Yue-mao 

机构地区：[1]Engineering Research Center of Industrial Microbiology, Ministry of Education, Engineering Research Center of Fujian Modern Fermentation Technology, College of Life Sciences, Fujian Normal University, Fuzhou 350108, P. R. China [2]School of Pharmaceutical Sciences, Shandong University, Jinan 250012, P. R. China [3]School of Life Sciences, Xiamen University, Xiamen 361005, P. R. China

出　　处：《Chemical Research in Chinese Universities》2012年第6期976-979,共4页高等学校化学研究（英文版）

基　　金：Supported by the Basic Research Development Program of China(No.2010CB833802)

摘　　要：Two new marasmone derivatives,1α,2β-dihydroxymarasmone（1） and 2β,3α-dihydroxymarasmone（2）,and one new norsesquiterpenoid,14-hydroxyoreadone（3）,were obtained from the fermentation broth of Agrocybe sp.,together with three known sesquiterpenes,agrocybolacton（4）,marasmene（5） and 14-hydroxymarasmene（6）.Their structures were elucidated by spectroscopic analyses,including 1D-and 2D-NMR experiments,high resolution electron spray ionization quadrupole time of flight（HR-ESI-Q-TOF） mass spectrometry,chemical correlation,X-ray single crystal diffraction and also compared with reported data.Two new marasmone derivatives,1α,2β-dihydroxymarasmone（1） and 2β,3α-dihydroxymarasmone（2）,and one new norsesquiterpenoid,14-hydroxyoreadone（3）,were obtained from the fermentation broth of Agrocybe sp.,together with three known sesquiterpenes,agrocybolacton（4）,marasmene（5） and 14-hydroxymarasmene（6）.Their structures were elucidated by spectroscopic analyses,including 1D-and 2D-NMR experiments,high resolution electron spray ionization quadrupole time of flight（HR-ESI-Q-TOF） mass spectrometry,chemical correlation,X-ray single crystal diffraction and also compared with reported data.

关 键 词：SESQUITERPENOID Agrocybe sp. Marasmone derivative 

分 类 号：O624.13[理学—有机化学] O614.813[理学—化学]