隔药灸治疗原发性痛经疗效及对PGF_(2α)/PGE_2的影响  

Clinical Effect of Medicine-separated Moxibustion on Primary Dysmenorrhea and Its Influence on PGF_(2α)/PGE_2

作　　者：陈日兰[1] 姬乐[1] 苗芙蕊[1] 邓朋翼[2] 周丽君[2] 朱英[1] 

机构地区：[1]广西中医学院附属瑞康医院,广西南宁530011 [2]广西中医学院,广西南宁530011

出　　处：《辽宁中医药大学学报》2013年第1期19-21,共3页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：广西中医药管理局广西卫生厅中医药科技专项课题(gzzc0924);广西教育厅科研立项项目(200911LX245)

摘　　要：目的:探讨隔药灸神阙穴治疗原发性痛经的疗效机制。方法:把90例原发性痛经患者按随机数字表分为3组各30例,分别是隔药灸组、隔盐灸组、西药组,并设正常空白对照组。结果:隔药灸组(总有效率96.7%)与隔盐灸组(总有效率90.0%)、隔盐灸组与西药组(76.7%)疗效比较,P<0.05;隔盐灸组与西药组疗效比较,P<0.01。隔药灸组与隔盐灸组、隔盐组与西药组治疗后PGF2α比较,P<0.05;隔药灸组与西药组治疗后PGF2α比较,P<0.01。隔盐组与西药组治疗后PGE2比较,P<0.05;隔药灸组与隔盐灸组、隔药灸组与西药组治疗后PGE2比较,P<0.01。隔药灸组、隔盐灸组、西药组治疗前的PGF2α、PGE2指标与正常空白组比较,P<0.01。结论:灸法治疗痛经的疗效优于口服药物,且隔药灸疗效显著,其作用机制可能与降低经期外周血PGF2α含量,升高PGE2含量,降低PGF2α/PGE2有关。Objective：Discussion on mechanism of medicine-separated moxibustion on Shenque piont treating primary dysmenorrhea was made.Methods：90 cases of primary dysmenorrhea patients were randomly divided into 3 groups with 30 cases in each group：salt-separated moxibustion group,medicine-separated moxibustion group,group of Western medicine,and a blank control group.Result：Comparisons of medicine-separated moxibustion group（total effective rate was 96.7%）and the salt-separated moxibustion group（total effective rate was 90.0%）,the salt-separated moxibustion group and the Western group（76.7%）had significance（P0.05）.Comparison of salt-separated moxibustion group and Western medicine group had significance（P0.01）.PGF2α comparison of medicine-separated moxibustion group and the salt-separated group as well as the PGF2α comparison of salt-separated moxibustion group and Western medicine group after treatment had significance（P0.05）.PGF2α in medicine-separated moxibustion group compared with that in Western medicine group after treatment,there was significance（P0.01）.PG2α in salt-separated moxibustion group compared with that in Western medicine group after treatment,there was significance（P0.05）.PGE2 comparison between medicine-separated moxibustion group and salt-separated moxibustion group as well as that between medicine-separated moxibustion group and Western medicine group had significance（P0.01）.PGF2α and PGE2 in medicine-separated moxibustion group,salt-separated moxibustion group and Western medicine group compared with those in blank control group,there was significance（P0.01）.Conclusion：Moxibustion therapy is superior to oral medication for treating primary dysmenorrhea and medicine-separated moxibustion has obvious effect.Its mechanisms may be related to reducing menstrual PGF2α content in peripheral blood,elevating PGE2 concentration and reducing PGF2α/PGE2.

关 键 词：隔药灸 神阙穴 前列腺素 

分 类 号：R271.113[医药卫生—中医妇科学]