IL-17家族与气道慢性炎症性疾病  

IL-17 cytokine family and chronic airway inflammatory diseases

作　　者：徐敏[1] 吴开松[2] 

机构地区：[1]武汉大学基础医学院武汉铁路职业技术学院护理学院,430205 [2]武汉大学中南医院呼吸内科

出　　处：《国际免疫学杂志》2013年第1期45-48,共4页International Journal of Immunology

摘　　要：气道慢性炎症性疾病如慢性阻塞性肺疾病、支气管哮喘等是在各种内外界刺激因素作用下由气道固有细胞、炎症细胞和炎症因子参与的非特异性炎症性疾病。目前，人们已经发现6个IL-17家族成员，它们在慢性气道炎症性疾病的发展中发挥重要作用。故深入认识IL-17家族与慢性气道炎症性疾病的关系将为临床治疗提供新的思路。Chronic airway inflammatory diseases, such as chronic obstructive pulmonary disease and bronchial asthma, are non-specific inflammatory diseases, in which airway intrinsic cells, inflammatory cells and cytokines involved under various internal and external stimuli factors. So far, 6 members of IL-17 cytokine family have already been described, playing crucial roles in the development of the chronic airway inflammatory diseases. Therefore, further study on the relationship between IL-17 cytokine family and the chronic airway inflammatory diseases will provide new ideas for the treatment of these diseases.

关 键 词：IL-17家族 气道慢性炎症 慢性阻塞性肺疾病 支气管哮喘 

分 类 号：R5[医药卫生—内科学]