对2010年版《中国药典》(二部)中盐酸普鲁卡因注射液鉴别试验(1)的探讨  

Exploration of Identification Test(1) of Procaine Hydrochloride Injection in 2010 Edition of Chinese Pharmacopeia(Ⅱ)

作　　者：石天松 

机构地区：[1]南宁食品药品检验所,南宁530001

出　　处：《中国药房》2013年第1期74-75,共2页China Pharmacy

摘　　要：目的:对2010年版《中国药典》(二部)所收载的盐酸普鲁卡因注射液鉴别试验(1)提出修改建议。方法:对盐酸普鲁卡因注射液中鉴别试验(1)所包含的氯化物鉴别试验、芳香第一胺类鉴别试验与附录Ⅲ一般鉴别试验的方法进行分析比较,并以实际操作进行验证。结果与结论:盐酸普鲁卡因注射液中氯化物及芳香第一胺类鉴别试验标准过于简化,不够明确,并因层层转述导致与附录Ⅲ的相关内容不一致。建议应将盐酸普鲁卡因注射液鉴别试验(1)标准描述重新拆分并使之具体化、一致化、明确化。OBJECTIVE：To put forward some suggestions for the improvement of identification test（1）of Procaine hydrochloride injection in Chinese Pharmacopeia（Ⅱ）（2010 edition）.METHODS：The identification test（1）of Procaine hydrochloride injection,including chloride identification test,first aromatic amine identification test,were analyzed and compared with general identification test in appendix Ⅲ,and then checked by practical experience.RESULTS CONCLUSIONS：The identification standard of chloride and first aromatic amine in Procaine hydrochloride injection were too simplified,not clear,and reported at all levels so that it was inconsistent with relevant content of appendix Ⅲ.It ought to split the description of identification test（1）standard for Procaine hydrochloride injection again,and make it more specific,consistent and clear.

关 键 词：2010年版《中国药典》 盐酸普鲁卡因注射液 氯化物 芳香第一胺 鉴别试验 探讨 

分 类 号：R927[医药卫生—药学]