中枢神经系统感染患儿髓鞘碱性蛋白的检测及分析  

Measurement and analysis of myelin basic protein in children with central nervous system infection

作　　者：麦坚凝[1] 何馨[1] 杨思达[1] 何旦莎[2] 夏学峰 

机构地区：[1]广州市儿童医院神经康复科,510120 [2]广州医学院神经疾病研究所实验室,510182

出　　处：《中国实用儿科杂志》2000年第4期223-224,共2页Chinese Journal of Practical Pediatrics

摘　　要：目的　评价髓鞘碱性蛋白 (MBP)在小儿中枢神经系统病毒和细菌感染中的临床意义。方法　对 48例中枢神经系统感染性疾病患儿血清及脑脊液 (CSF)的MBP进行定量检测。结果　病毒性感染组与细菌性感染组血清和CSF中MBP水平较对照组显著升高 (P <0 0 0 1)。Objective To evaluate the clinical significance of myelin basic protein(MBP)in children with central nervous system(CNS)viral and bacterial infection.Methods The ELISA method was used to analyze the level of MBP in the serum and CSF of 48 children with CNS infection.Results The level of MBP in the serum and CSF in both CNS viral and bacterial infections was higher than those in the controlled group(P<0\^001).Conclusion MBP level in the serum and CSF could be a diagnostic sign of CNS infections.

关 键 词：髓鞘碱性蛋白 儿童 中枢神经系统感染 

分 类 号：R725.152[医药卫生—儿科] R725.123[医药卫生—临床医学]