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机构地区:[1]中国康复研究中心北京博爱医院呼吸内科,北京市100068 [2]首都医科大学康复医学院,北京市100068
出 处:《中国康复理论与实践》2012年第12期1131-1134,共4页Chinese Journal of Rehabilitation Theory and Practice
基 金:中央级公益性科研院所基本科研业务费专项资金(2012CZ-12)
摘 要:目的探讨摄氧效率斜率(OUES)评价慢性阻塞性肺疾病(copo)患者心肺功能的价值。方法对54例肺功能Ⅱ~Ⅳ级的稳定期COPD患者进行运动心肺功能的评价,采用症状限制性Steep分级平板运动方案,同时测定摄氧量(VO2)、二氧化碳排出量(VCO2)、峰值摄氧量(VO2pek)、每分通气量(VE)、呼吸气体交换率(RER)。采用对数曲线拟合的方法,分析递增负荷运动试验中VO2与VE之间的关系,建立回归方程VO2=algVE+b,计算摄氧效率斜率(OUES),即a。同时测定无氧阈(VAT)。结果OUES与VO2pek呈显著正相关(均P〈0.001)。75%OUES、90%OUES、100%OUES三者均值无显著性差异(辟0.239,P=0.830)。结论OUES可以反映COPD患者运动心肺功能,75%OUES可以作为亚极量运动水平心肺功能的评价指标。Objective To investigate the efficacy of oxygen uptake efficiency slope (OUES) on evaluation the cardiopulmonary function of patients with chronic obstructive pulmonary disease (COPD). Methods The cardiopulmonary function of 54 stable COPD patients with the cardiopulmonary function of II -W were evaluated, following a symptom-limited Steep protocol with simultaneous respiratory gas mea- surement, they were performed exercise tests on a treadmill, simultaneously the oxygen uptake (VO2), carbon dioxide production (VCO2), peak oxygen uptake (VOapoak), minute ventilation (VE), and respiratory gas exchange rate (RER) were measured. OUES was derived from the relation between VO2 and VE during incremental exercise and was determined by VO2=algVE+b, where a=OUES, to measure anaerobic threshold (VAT) meanwhile. Results OUES correlated with the VO2p,k (P〈0.001). 75% OUES, 90% OUES and 100% OUES were not signif- icantly different (F=0.239, P=0.830). Conclusion OUES can respond the cardiopulmonary function in patients with COPD, 75% OUES from sub-maximal exercise can be an index for cardiopulmonary function.
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