血清氮端脑钠肽水平在老年慢性心力衰竭患者左心功能评估中的价值  

Value of serum N terminal brain natriuretic peptide level on left ventricular function assessment of elderly patients with chronic heart failure in patients

作　　者：马文杰[1] 何秀兰[1] 罗良贤[2] 

机构地区：[1]湖南省郴州市第一人民医院南院老年医学科,湖南郴州423000 [2]湖南省郴州市第一人民医院南院ICU,湖南郴州423000

出　　处：《中国医药导报》2012年第34期58-59,共2页China Medical Herald

摘　　要：目的探讨老年慢性心力衰竭患者左心室舒缩功能与血清NT-proBNP水平的关系。方法选择老年慢性心力衰竭患者84例,分为以舒张功能异常为主的Di组和以收缩功能异常为主的Co组,对照组选择体健老年人30例,检测三组血清NT-proBNP水平并分析其与左心室射血分数(LVEF)以及峰速度比值(E/A)之间的关系。结果与对照组比较,Di组及Co组患者血清NT-proBNP水平均显著升高,差异均有统计学意义(均P<0.05);NT-proBNP水平与LVEF呈负相关(r=-0.677,P=0.018),与E/A亦呈负相关(r=-0.240,P=0.024)。结论血清NT-proBNP可用于判断老年慢性心力衰竭患者左心室舒张与收缩功能。Objective To explore correlations between left ventricular systolic and diastolic functions and serum level of NT-ProBNP in elderly patients with chronic heart failure.Methods 84 elderly patients with CHF were selected and divided into Di group（Diastolic dysfunction） and Co group（abnormal systolic function）,30 cases of health people were selected as control group at the same time.Serum levels of NT-proBNP were detected and relationships with LVEF and E/A were analyzed.Results Compared with control group,levels of NT-proBNP was higher in the Di group and Co group,there were all significant differences（all P0.05）.Negative correlations were found between serum levels of NT-proBNP and LVEF（r =-0.677,P=0.018） and E/A（r =-0.240,P=0.024）.Conclusion Serum level of NT-ProBNP can help assess o left ventricular systolic and diastolic functions in elderly patients with CHF.

关 键 词：慢性心力衰竭 老年 氨基末端脑钠肽 

分 类 号：R541[医药卫生—心血管疾病]