相位对比电影MRI在乙状窦血流测量中的初步研究  被引量:2

Preliminary study of phase-contrast cine MRI in measurement of sigmoid sinus blood flow

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作  者:刘兆会[1] 龚树生[2] 胡凌[1] 赵鹏飞[1] 王振常[1] 王国鹏[2] 鲜军舫[1] 马晓波[2] 李轶[2] 

机构地区:[1]首都医科大学附属北京同仁医院影像中心,北京100730 [2]首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,北京100730

出  处:《磁共振成像》2012年第6期410-414,共5页Chinese Journal of Magnetic Resonance Imaging

基  金:国家自然科学基金(81171311);北京市教委科技发展重点项目(KZ20110025029);北京市科委首都临床特色项目(D101100050010031)资助

摘  要:目的探讨应用相位对比电影MRI(PC cine MRI)定量测量乙状窦血流的可行性。材料与方法应用PC cine MRI测量20名正常志愿者双侧乙状窦正向峰值流速(PPV)、反向峰值流速(PNV)、平均每搏血流量(AFV/B)、正向平均每搏血流量(APFV/B)、反向平均每搏血流量(ANFV/B)。根据上述测量结果及心率、乙状窦截面积计算平均每分血流量(AFV/M)、正向平均每分血流量(APFV/M)、反向平均每分血流量(ANFV/M)、正向平均流速(APV)、反向平均流速(ANV)及反流分数(RF)。结果左右侧乙状窦PPV分别是:(24.7±7.4)cm/s、(29.8±4.7)cm/s;APV:(10.6±2.9)cm/s、(15.7±3.3)cm/s;APFV/B:(3.8±2.0)ml/beat、(5.2±2.0)ml/beat;APFV/M:(252.3±125.4)ml/min、(345.5±125.8)ml/min;AFV/B:(3.8±2.0)ml/beat、(5.1±1.9)ml/beat;AFV/M:(250.9±126.4)ml/min、(335.4±117.0)ml/min。右侧乙状窦PPV和APV均明显大于左侧(P<0.05),而左右侧APFV/B、APFV/M、AFV/B和AFV/M差异均无统计学意义(P>0.05)。左右侧乙状窦PNV四分位间距分别是:0.2~34.3cm/s、0~34.4cm/s,ANV:0~0.3cm/s、0~1.0cm/s,ANFV/B:0~0.1ml/beat、0~0.4ml/beat,ANFV/M:0~6.5ml/min、0~30ml/min,RF:0%~2.7%、0%~6.3%。左右侧上述反向血流指标测量值差异均无统计学意义(P>0.05)。结论 PC cine MRI可用于定量测量乙状窦血流动力学指标。Objective:To research the feasibility of measuring hemodynamic information of sigmoid sinus with phase-contrast cine MRI(PC cine MRI) in vivo.Materials and Methods:Twenty healthy adult volunteers underwent MR examination.The velocity encoded PC cine MRI was applied to measure the hemodynamic parameters in the middle of bilateral sigmoid sinus,including the peak positive velocity(PPV),peak negative velocity(PNV),average flow volume per beat(AFV/B),average positive flow volume per beat(APFV/B),and the average negative flow volume per beat(ANFV/B).On the basis of above measured hemodynamic parameters,heart rate(HR),and the cross sectional area of sigmoid sinus,the average flow volume per minute(AFV/M),average positive flow volume per minute(APFV/M),average negative flow volume per minute(ANFV/M),average positive velocity(APV),average negative velocity(ANV),and the regurgitation fraction(RF) were calculated.Results:The PPV of the left and right sigmoid sinus were(24.7±7.4) cm/s,(29.8±4.7) cm/s respectively,the APV(10.6±2.9) cm/s,(15.7±3.3) cm/s,the APFV/B(3.8±2.0) ml/beat,(5.2±2.0) ml/beat,the APFV/M(252.3±125.4) ml/min,(345.5±125.8) ml/min,the AFV/B(3.8±2.0) ml/beat,(5.1±1.9) ml/beat,and AFV/M(250.9±126.4) ml/min,(335.4±117.0) ml/min.The interquartile range of PNV of left and right sigmoid sinus were 0.2—34.3 cm/s,0—34.4 cm/s respectively,ANV 0—0.3 cm/s,0—1.0 cm/s,ANFV/B 0—0.1 ml/beat,0—0.4 ml/beat,ANFV/M 0—6.5 ml/min,0—30 ml/min,and RF 0%—2.7%,0%—6.3%.There were statistically significant increase of the PPV and APV on the right sigmoid sinus without statistically significant differences in other hemodynamic parameters between left and right sigmoid sinus.Conclusion:The hemodynamic parameters in sigmoid sinus can be measured with PC cine MRI.

关 键 词:颅窦 血液动力学现象 磁共振成像 

分 类 号:R445.2[医药卫生—影像医学与核医学] R743[医药卫生—诊断学]

 

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