MRI与HLA-B_(27)诊断强直性脊柱炎骶髂关节病变的联合应用  

The Combination of MR Imaging and HLAB_(27) on the Diagnosis of Sacroiliac Joints Lesions in Ankylosing Spondylitis

作　　者：王东[1] 江华堂[1] 陈武标[1] 吴永峻[1] 

机构地区：[1]广东医学院附属医院放射科,广东湛江524001

出　　处：《中国CT和MRI杂志》2012年第6期94-96,112,共4页Chinese Journal of CT and MRI

摘　　要：目的探讨MRI与HLA-B27联合对诊断强直性脊柱炎(AS)骶髂关节(SIJ)病变的临床应用价值。方法回顾性分析48例经临床确诊的AS的MRI和HLA-B27检测资料,并比较MRI与MRI联合HLA-B27对ASSIJ病变诊断的阳性率。结果 48例AS病例中,MRI检查诊断AS的阳性率为79.2%;HLA-B27检测阳性率为89.6%;MRI联合HLA-B27检测阳性为91.7%;MRI联合HLA-B27诊断AS的阳性率高于单纯MRI检查组,其差异有统计学意义(X2=11.759,P<0.01)。结论 MRI与HLA-B27联合可提高AS诊断的阳性率,有利于AS的早期发现、及时治疗。Objective To investigate the clinical value of combination of MR imaging and HLA-B27 on the diagnosis of sacroiliac joints （SIJ） lesions in ankylosing spondylitis （AS）. Methods The MRI and HLA-B27 data of 48 AS cases proved by clinical examination were retrospectively analyzed. The positive rates in detecting the SIJ lesions of AS were com- pared between MRI and combination MRI and HLA-B,r Results Among the 48 patient of AS, the positive rate of MRI diagnosis was 79.2%, the positive rate of HLA-B27 examina- tion was 89.6%, the positive rate of MRI combined with HLA-B_~7 was 91.7%. The positive rate of MRI combined with HLA-B27 was higher than that of MRI. which were showing significant difference （X2=11.759, P 〈 0.01 ）. Conclusion The combination of MRI and HLA-B27 examination can increase the positive rate of AS diagnosis, which may be helpful for AS early detection and prompt treatment.

关 键 词：骶髂关节 强直性脊柱炎 磁共振成像 HLA-B27 

分 类 号：R593.23[医药卫生—内科学] R445.2[医药卫生—临床医学]