萎缩性骨折不愈合的研究新进展  

New research progress on atrophic nonunion

作　　者：魏均强[1,2] 张伯勋[1] 陈华[1] 唐佩福[1] 王岩[1] 

机构地区：[1]解放军总医院骨科专科医院,北京100853 [2]解放军总医院急救部,北京100853

出　　处：《中国骨伤》2012年第12期1053-1056,共4页China Journal of Orthopaedics and Traumatology

基　　金：国家自然科学基金项目(编号:81000803);北京市自然科学基金项目(编号:7083114)~~

摘　　要：萎缩性骨折不愈合形成是一个复杂过程,既往研究认为萎缩性骨折不愈合主要是由于骨折断端血运缺乏引起,但也有研究发现萎缩性骨折不愈合的中晚期血运并不缺乏,更可能是由于早期成骨性因素降低和血运减少引起,具体发病机制有待进一步研究。目前有效治疗萎缩性骨折不愈合的措施,主要有植骨和固定、物理治疗、局部注射疗法等。多方位的预防则能有效减少萎缩性骨折不愈合的发生,但萎缩性骨折不愈合仍是骨科临床工作中的棘手问题,应给予充分的重视,并进行合理有效地防治。本文通过回顾分析近年萎缩性骨折不愈合的相关文献,对萎缩性骨折不愈合相关的病因、诊断和防治措施作一综述。Occurance of atrophic nonunion is a complex process. Previous studies suggested that atrophic nonunion was mainly due to lack of blood supply of fracture fragments, but recent studies found that blood supply was not deficiency in mid- dle and late stages, indicating that decreased osteogenic factors and blood supply in early stages might play an important role in morbidity. Current effective treatment measures for atrophic nonunion mainly include bone graft and fixation, physical therapy, local injection therapy. All-round preventive could reduce incidence of atrophic nonunion. Atrophic nonunion is still a trouble- some complication of fractures in orthopaedics, and more attention should be paid for its effective prevention and treatment. The paper summarized recent original articles about atrophic nonunion and reviewed the occurrence mechanisms ,diagnosis, prevention and treatment measures of this disease.

关 键 词：骨折 骨折 不愈合 综述文献 

分 类 号：R683.42[医药卫生—骨科学]