中药干预气虚血瘀型慢性心衰治疗的增效减毒作用研究  

Research on synergism and attenuation effect about intervention of traditional Chinese medicine in the treatment of chronic heart failure with Qi deficiency and blood stasis syndrome

作　　者：张艳[1] 王辰[1] 白颖舜 

机构地区：[1]辽宁中医药大学附属医院,沈阳110032 [2]本溪市中医院,本溪117000

出　　处：《中华中医药杂志》2013年第1期82-84,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家"十一五"科技支撑计划项目(No.2007BAI20B076)~~

摘　　要：目的:评价常规西药加用参草通脉颗粒治疗慢性心衰的增效减毒作用,为制订中医药干预慢性心衰的临床治疗方案提供循证医学证据。方法:收集慢性心衰患者共280例,随机分为两组,一组为对照组,采用西医常规治疗;另一组为治疗组,采用西医常规治疗加用参草通脉颗粒,疗程均为3个月。观察患者的总体疗效及药物减停情况。结果:治疗组与对照组显效率分别为61.59%、32.28%,总有效率分别为95.65%、70.87%,治疗组明显优于对照组(P<0.01);治疗组与对照组停药率分别为42.03%、25.20%,停减率分别为63.04%、47.25%,治疗组明显优于对照组(P<0.01)。结论:中医药干预慢性心衰治疗有明显的增效减毒作用。Objective： To evaluate the conventional western medicine combined with Shencao Tongmai Granule in treating chronic heart failure synergism and attenuation effect.For the development of traditional Chinese medicine intervention for chronic heart failure clinical treatment plan provides the evidence of evidence-based medicine.Methods： The data of 280 cases of chronic heart failure,were randomly divided into two groups,one group was the control group with routine treatment of western medicine;another group was treated by routine treatment of western medicine combined with Shencao Tongmai Granules,the treatment course is 3 months.Patients were observed for overall efficacy and drug withdrawal condition.Results： The effective rate of treatment group and the control group was respectively 61.59%,32.28%;the total effective rate were 95.65%,70.87%,there was significant difference（P0.01）,the withdrawal rates of treatment group and the control group were 42.03%,25.20%;the withdrawal and reduction rate respectively were 63.04%,47.25%,there was significant difference（P0.01）.Conclusion： Intervention of traditional Chinese medicine in treatment of chronic heart failure have obvious synergistic attenuation effect.

关 键 词：参草通脉颗粒 慢性心衰 增效减毒 

分 类 号：R259[医药卫生—中西医结合]