脐疗对脾虚型肠易激综合征患者血清脑肠肽水平的影响  

Effect of navel treatment on serum brain-gut peptide level in the irritable bowel syndrome patients with spleen deficiency

作　　者：杨肖敏[1,2] 刘存志[1] 石广霞[1] 马玉侠[3] 高树中[3] 王秀英[3] 

机构地区：[1]首都医科大学附属北京中医医院,北京100010 [2]天津中医药大学2009级硕士研究生,天津300193 [3]山东中医药大学,济南250355

出　　处：《中华中医药杂志》2013年第1期262-264,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家重点基础研究发展计划(973计划)(No.2007CB512703)~~

摘　　要：目的:探讨脐疗对脾虚型肠易激综合征(IBS)患者血清脑肠肽含量的影响。方法:33例患者随机分为隔药物灸脐组(11例)、隔淀粉灸脐组(11例)和西药对照组(11例),治疗4周为1个疗程。治疗前后采用ELISA法检测患者血清P物质(SP)、血管活性肠肽(VIP)和5-羟色胺(5-HT)的含量。结果:治疗后与隔淀粉灸脐组、西药对照组比较,隔药物灸脐组患者血清SP、VIP和5-HT含量明显下降(P<0.01),隔淀粉灸脐组与西药对照组比较,差异无统计学意义。结论:脐疗可通过降低IBS患者血清SP、VIP和5-HT含量,发挥治疗作用。Objective： To explore the effect of navel treatment on serum brain-gut peptide of the irritable bowel syndrome patients with spleen deficiency.Methods： 33 patients were randomly divided into 3 groups.One group was treated with drug-separated moxibustion at the navel（n=11）,the second group was treated with starch-separated moxibustion at the navel（n=11） and the third group was treated with western medicine（n=11）.All patients were treated for 4 weeks.The contents of serum substance P,active bowel peptide and serotonin were detected by ELISA before and after treatment.Results： Compared with the starch-separated moxibustion at the navel and western medicine,the content of serum substance P,active bowel peptide and serotonin were reduced in the group of drug-separated moxibustion at the navel after treatment（P0.01）.But no significant difference was found between starch-separated moxibustion at the navel and western medicine group.Conclusion： Navel treatment could reduce the content of serum substance P,active bowel peptide and serotonin and improve the bowel function in the irritable bowel syndrome patients.

关 键 词：肠易激综合征 脐疗 脑肠肽 

分 类 号：R246.1[医药卫生—针灸推拿学]