江苏省部分地区棘球蚴病流行现状调查  

Epidemiological survey of echinococcosis in some areas of Jiangsu Province

作　　者：徐祥珍[1] 金小林[1] 江文才[1] 曹汉钧[1] 沈明学[1] 高琪[1] 吕来福 陈建农[3] 

机构地区：[1]江苏省寄生虫病防治研究所,无锡214064 [2]江苏省溧阳市疾病预防控制中心 [3]江苏省宜兴市疾病预防控制中心

出　　处：《中国血吸虫病防治杂志》2012年第6期697-699,共3页Chinese Journal of Schistosomiasis Control

基　　金：江苏省卫生厅科研项目(H200869;X200929)

摘　　要：目的了解江苏省部分地区棘球蚴病流行情况。方法采用回顾性调查和病例线索调查确定病例感染情况;对疑似本地感染病例所在自然村所有犬粪进行免疫学粪抗原检测,采用Kato-Katz法检测粪抗原阳性犬粪;对疑似本地感染病例的周围重点人群、所在乡(镇)部分7～12岁小学生以及所在县(市、区)随机抽取5个不同方位的乡(镇)部分7～12岁学生进行病例扩大搜索,采用酶标记免疫血清学和点免疫胶体金渗滤法双重检测血清棘球蚴病抗体;对抗体阳性者采用影像学方法验证。结果共发现索到10例输入性棘球蚴病病例,16例疑似本地感染病例。对病例所在自然村1 938份犬粪样本检测,阳性20份,阳性率为1.03%,病原学检测未发现阳性。血清学检测重点人群及小学生共12 473份,阳性72份,阳性率为0.58%;抗体阳性者影像学检测未见囊型结节。结论无直接证据表明江苏省有棘球蚴病传染源及疫源地存在;但需做好棘球蚴病防治监测工作。Objective To understand the prevalence of echinococcosis in some areas of Jiangsu Province,so as to provide the evidence for making practical control measures.Methods The cases were determined by a retrospective survey and case-clues survey.All canine feces were tested by immunological fecal antigen in the villages of the local infection suspected cases.The antigen-positive feces were detected for E.chinococcus eggs by Kato-Katz technique.A serological investigation was administrated to search infected persons by double methods of enzyme-labeled immune assay and point immuno-gold filtration assay in the focus groups around the local infection suspected cases,and some students aged from seven to twelve years in their townships and in five different-orientation townships sampled randomly in their counties.The antibody-positive people were confirmed further by using imaging detection.Results There were 10 imported cases and 16 local infection suspected cases.Twenty canine feces were positive among 1 938 samples,and the positive rate was 1.03%.However,no pathogen was found.Of 12 473 serum samples,72 were positive in sera immunological antibody test（0.58%）,but no cystic nodules were found by imaging detection.Conclusion There is no direct evidence for confirming the presence of infectious source and foci of echinococcosis in Jiangsu Province.However,the surveillance of echinococcosis is still needed.

关 键 词：棘球蚴病 流行病学 传染源 江苏省 

分 类 号：R532.32[医药卫生—内科学]