复方樟柳碱治疗视神经损伤48例临床疗效分析  

Clinical efficacy analysis on compound Anisodine in treatment of optic nerve injury in 48 cases

作　　者：颜美荣[1] 李正贤[1] 周一鸣[1] 彭晓[1] 张景瑶[1] 佘永川[1] 张玉[1] 

机构地区：[1]解放军第163医院眼科,湖南长沙410003

出　　处：《临床军医杂志》2012年第6期1482-1484,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨复方樟柳碱治疗视神经损伤的方法及临床疗效。方法将48例视神经损伤患者,随机分为两组:治疗组24例(24眼),采用复方樟柳碱治疗;对照组24例(24眼),使用血管扩张剂,营养视神经的药物,B族维生素等治疗。全部患者早期均给予皮质类固醇和甘露醇。结果治疗组显效8例,有效12例,无效4例。对照组显效4例,有效9例,无效11例。治疗组、对照组总有效率分别为83.3%、54.1%。两组比较,差异有统计学意义(χ2=4.19,P<0.05)。结论复方樟柳碱治疗视神经损伤疗效显著,使用方便。Objective To investigate the treatment methods and clinical efficacy of compound Anisodine in treating optic nerve injury. Methods Forty eight cases of optic nerve injury were randomly divided into two groups.24 cases（24 eyes） in the treatment group were treated with compound Anisodine.24 cases（24 eyes） in the control group were treated by vasodilators,optic nerve nutrition drugs,vitamins B,et al.All patients were given early corticosteroids and mannitol. Results 8 cases were markedly effective,12 effective and 4 ineffective in the treatment group.The control group,markedly effective,effective and ineffective were 4 cases,9 cases and 11 cases respectively.The total effective rates of treatment group and control group were 83.3% and 54.1% respectively.There was statistical significant difference between two groups（χ2=4.19,P0.05）. Conclusion The compound Anisodine has remarkable effect in treatment of optic nerve injury.It is convenient to use.

关 键 词：视神经损伤 复方樟柳碱 治疗 

分 类 号：R774.6[医药卫生—眼科]