秃疮花水溶性外用制剂抗病毒试验  

Antiviral Test on Dicranostigma leptopodum(Maxim) Fedde of Water Soluble Preparation for External Use

作　　者：党岩[1] 马志宏[1] 苟想珍[1] 孙春香[1] 常亮[1] 李引乾[2] 杨鸣琦[2] 陈德坤[2] 秦大卫[3] 

机构地区：[1]甘肃省畜牧兽医研究所,甘肃平凉744000 [2]西北农林科技大学动物医学院 [3]甘肃省农村能源办公室

出　　处：《畜牧兽医杂志》2013年第1期3-5,共3页Journal of Animal Science and Veterinary Medicine

基　　金：甘肃省科学事业费项目(QS061-C31-05)

摘　　要：为了确定秃疮花水溶性外用制剂的临床应用剂量标准,试验用甘肃省畜牧兽医研究所研制的秃疮花水溶性外用制剂,以Reed-Muench法进行了体外抗病毒试验。试验结果表明秃疮花水溶性外用制剂对GPV的IC50=2-6.5倍个外用制剂试验单位(8.8mg/mL外用制剂干物质);对CPDV的IC50=2-7.2倍个外用制剂试验单位(5.4mg/mL外用制剂干物质)。这说明秃疮花水溶性外用制剂对GPV和CPDV有一定的抑制功能。Antiviral test in vitro using Reed-Muench method was conducted to determine clinical dose standard for Dicranos- tigma leptopodum （Maxim） Fedde of water soluble preparation for external use （development by Gansu Institute of Animal Sci- ence and Veterinary Medicine）. The results demonstrated that the half inhibitory concentrations （IC50） for GPV and CPDV were IC50 = 2-6.5 times as a topical-preparations test unit （8.8 mg/mL topical-preparations dry matter） and IC50 = 2-7.2 times as a topical-preparations test unit （5.4 mg/mL topical-preparations dry matter） . This proved that the preparation had certain antiviral function for GPV and CPDV.

关 键 词：秃疮花 水溶性外用制剂 半数致死量 

分 类 号：S816.5[农业科学—饲料科学]