释放吲哚美辛的固定式铜宫内节育器对子宫出血影响的比较研究  

The Comparative Study on the Influence of Indomethacin releasing FCu-IUD on Uterine Bleeding

作　　者：李万[1] 曹路敏[1] 吴昌杰[1] 肖邦宙 肖秀梅 陈莉[1] 周玉玲[1] 

机构地区：[1]同济医科大学计划生育研究所,武汉430030 [2]武汉钢铁公司妇幼保健所,武汉430080

出　　处：《同济医科大学学报》2000年第3期223-225,共3页Acta Universitatis Medicinae Tongji

基　　金：湖北省科委"九五"重点科技资助项目!(No.961P190 1)

摘　　要：比较观察了两种宫内节育器 (FICu- IUD、FCu- IUD)对妇女子宫出血和体内贮备铁的影响 ,通过生殖激素测定排除了 FICu- IUD对生殖内分泌的影响。结果发现 :1临床观察中 FICu- IUD组经量增多、经期延长者较 FCu- IUD组减少 ,个别妇女的经血量 (MBL)甚至少于置器前。 2 MBL、 Hb、血清铁蛋白 (SF)测定显示 ,FICu- IUD组妇女MBL 较 FCu- IUD明显减少 (P<0 .0 5 ) ;两组 Hb均在正常水平 ;SF水平也均在正常值范围内。 3FICu- IU D对促卵泡成熟激素 (FSH)、黄体生成激素 (L H)、雌二醇 (E2 )、黄体酮 (P)水平无影响。研究结果显示 :释放吲哚美辛的固定式铜宫内节育器减少子宫出血有效 。The influences of FICu IUD and FCu IUD on women's menstrual blood loss (MBL) and iron status were observed comparatively. Hormonal determination excluded the effect of FICu IUD on reproductive endocrine. The results showed:1) During the clinical observation, the women inserted FICu IUD with menorrhagia and menostaxis were less than those inserted FCu IUD. 2) In FICu IUD group MBL was significantly decreased as compared with that in Fcu IUC ( P <0.05). 3) Levels of FSH, LH, E2, P were not influenced by FICu IUD. It was suggested that in domethacin releasing FCu IUD in reducing uterine bleeding is efficacy and doesn't influence iron status and reproductive endocrine.

关 键 词：铜宫内节育器 吲哚美辛 子宫出血 

分 类 号：R169.41[医药卫生—公共卫生与预防医学] R971