八珍汤对艾滋病抗病毒治疗诱发高乳酸血症的作用  

Clinic Effects of Bazhen Decoction on Hyperlacticemia Induced by Antiretroviral Therapy for AIDS Patients

作　　者：唐宁新[1] 欧健[1] 黄绍标[2] 何琦[3] 秦英梅[2] 陈益芹[2] 刘燕芬[2] 李伟新[2] 黄金萍[2] 

机构地区：[1]广西南宁市第四人民医院中医科,南宁市530023 [2]广西南宁市第四人民医院感染科,南宁市530023 [3]广西南宁市第四人民医院信息科,南宁市530023

出　　处：《广西医学》2012年第12期1622-1624,共3页Guangxi Medical Journal

基　　金：广西南宁市重大专项项目(200901014C)

摘　　要：目的观察加味八珍汤对艾滋病抗反转录病毒治疗(ART)诱发高乳酸血症的作用。方法 70例艾滋病ART后出现高乳酸血症患者,采用抽签法随机分为两组,治疗组35例给予ART联合加味八珍汤,对照组35例给予ART并口服碳酸氢钠片,疗程为48个月。每6个月检测血乳酸1次,比较两组患者血乳酸值的变化。结果治疗乏力、四肢麻木、肌肉疼痛、趾痛临床症状评分明显少于对照组(P<0.05)。治疗组血乳酸值小于对照组(P<0.05)。结论加味八珍汤可在一定程度上缓解ART诱发的高乳酸血症。Objective To study the clinic effects of modified Bazhen decoction on hyperlacticemia induced by antiretroviral therapy（ART） for AIDS patients. Methods Seventy AIDS patients with hyperlacticemia after ART were randomly divided into two groups, of which, the study group of 35 patients underwent ART combined with modified Bazhen decoction,the control group of 35 patients were given ART integrated with oral sodium bicarbonate tablets. The duration was 48 months in the two groups. Blood lactic acid was tested every 6 months to compare the difference of the two groups. Results Scores for the study group concerning to fatigue, numbness of the extremities, muscle pain, toe pain were significantly lower than those of the control group（P 〈0. 05）. Blood lactic acid value of the study group was less than that of the control group（P 〈0.05 ）. Conclusion Modified Bazhen decoction has certain clinic effects on hyperlacticemia induced by ART for AIDS patients.

关 键 词：艾滋病 高乳酸血症 抗反转录病毒治疗 加味八珍汤 中草药 

分 类 号：R512.91[医药卫生—内科学]