湖北省黑热病流行态势的评估  

EVALUATION OF PREVALENT STATUS OF KALA-AZAR IN ENDEMIC AREA OF HUBEI PROVINCE *

作　　者：桂爱芳[1] 左胜利[1] 吴锦华[1] 桂希恩[2] 胡乐群[1] 杨连第[1] 张绍清[1] 

机构地区：[1]湖北省医学科学院寄生虫病防治研究所,武汉430079 [2]湖北医科大学附二医院,武汉430071

出　　处：《中国寄生虫学与寄生虫病杂志》2000年第3期170-172,共3页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：湖北省科委 1997年重点资助项目!(97B22)

摘　　要：[目的 ]复查湖北省自 1989年起陆续报告的 14例“黑热病”,及评估我省黑热病的流行现况。 [方法 ]复查“黑热病”患者的骨髓片、免疫学检查 (L DT、IFAT)、接种动物及真菌培养、媒介 (白蛉 )和保虫宿主 (犬 )的调查。[结果 ]除 1例输入的和 1例残存的皮肤型黑热病外 ,其余 12例为播散型荚膜组织胞浆菌病。1997～ 1999年在 9个地市的 2 3个县 (市 )的 2 5个乡镇进行了免疫学监测 ,对 13 890人采用利什曼素皮内试验 (L DT) ,阳性率 0 .0 0 7% ,40岁以下的人群无阳性。其中 175 6人作间接荧光抗体试验 (IFAT) ,结果均为阴性。在调查区内未发现中华白蛉。查犬 30 2只 ,未发现病犬。 [结论 ]湖北省已消灭黑热病 。Objective] To identify the diagnosis of 14 cases with “kala\|azar” previously reported in Hubei Province since 1989 and to evaluate the present status of the disease. [Methods] Bone marrow smear, immunological test (LDTand IFAT), mouse inoculation, fungi culture, vector ( Phlebotomus ) and reservoir host (dog) survey. [Results] Among the 14 cases, 12 cases were progressive disseminated histoplasmois, one was an imported case and another one was a remnant skin type“kala\|azar” case. An immunological survey was conducted during 1997～1999 in 25 townships located in 23 counties of 9 prefectures and cities. A total of 13 890 persons had been examined by LDT, the positive rate was 0\^07% , no positive case was found among the persons under 40 years of age. During the survey, 1 756 persons had been examined by IFAT, the results were negative .No Phlebotomus chinensis had been found in the surveyed area . A total of 302 dogs were examined, no sick dog had been found. [Conclusion]Kala\|azar has been eradicated in Hubei Province.

关 键 词：黑热病 流行病学 LDT IFAT 荚膜组织胞浆菌病 

分 类 号：R531.601[医药卫生—内科学]