日本血吸虫感染对小鼠雄性激素水平的影响(英文)  

EFFECT OF SCHISTOSOMA JAPONICUM INFECTION ON SERUM TESTOSTERONE LEVELS IN MICE

作　　者：贺宏斌[1] Nobuo Ohta Hitoshi Kawaguchi 

机构地区：[1]湖南省寄生虫病防治研究所,岳阳414000 [2]DepartmentofMedicalZoology

出　　处：《中国寄生虫学与寄生虫病杂志》2000年第3期173-175,共3页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：日本文部省厚生省及日美联合医学科学基金部分资助! (编号#084570 82,# H10-Sshinko-26)

摘　　要：[目的 ]研究日本血吸虫感染对 C5 7BL/ 6小鼠雄性激素的影响。[方法 ]应用放射免疫测定法检测实验感染日本血吸虫动物血清中雄性激素睾酮的水平。 [结果 ]感染日本血吸虫 45 d小鼠血清中睾酮的水平明显低于对照组。 [结论 ]日本血吸虫感染可导致小鼠宿主雄性激素睾酮水平显著降低。Objective] To determine the effect of Schistosoma japonicum infection on the testoterone level in the sera from male C57BL/6 mice. [Methods] Radioimmunoassay was used to examine testosterone levels in sera of 9 male mice experimentally infected with Schistosoma japonicum . [Results] The serum testosterone levels reduced significantly in all experimentally infected animals 45 days after infection, as compared with the uninfected controls. [Conclusion] Infection with Schistosoma japonicum decreases testosterone levels in the mouse host.

关 键 词：日本血吸虫病 雄性激素 放射免疫测定 实验研究 

分 类 号：R532.21[医药卫生—内科学]