1例头孢菌素类抗生素致意识障碍与凝血障碍病例分析  

Analysis of a Case of Consciousness Disturbance and Coagulation Disorders Induced by Cephalosporins

作　　者：胡健敏[1] 蓝宇频[2] 

机构地区：[1]福建漳州市中医院,福建漳州363000 [2]解放军第175医院,福建漳州363000

出　　处：《中国药房》2013年第2期183-185,共3页China Pharmacy

摘　　要：目的:探讨头孢菌素导致意识障碍以及凝血障碍的特点。方法:通过介绍1例肺部感染患者在应用头孢菌素类药物治疗过程中先后发生意识障碍以及凝血障碍的病例,结合相关资料从临床药师的角度阐明头孢菌素导致意识障碍及凝血障碍的成因及预防、治疗措施。结果:头孢菌素应用于老年肾功能不全患者时更易引发不良反应,故在临床应用中临床药师的及时干预能够最大程度地减少药源性伤害。结论:临床药师应利用所掌握的药学知识,充分发挥自己的业务专长,积极参与到临床治疗中,确保药物治疗安全有效。To investigate the feature of consciousness disturbance and coagulation disorders caused by cephalosporins. METHODS： A case of pulmonary infection patient who received the treatment of cephalosporin suffering from consciousness disturbance and coagulation was introduced. Causes, prevention and therapeutic scheme of consciousness disturbance and coagulation disorders caused by cephalosporins were interpreted from the perspective of clinical pharmacists based on relevant literatures. RESULTS： Cephalosporin is more prone to induce adverse drug reaction in the elderly patients with renal insufficiency. So, timely intervention given by the clinical pharmacists could reduce the drug-induced damage at utmost during application. CONCLUSION： Clinical pharmacists should fully use their available knowledge and specialized skills, and actively participate in clinical drug therapy to make sure the safety and efficacy of drug therapy.

关 键 词：头孢菌素 头孢噻利 头孢孟多 意识障碍 凝血障碍 临床药师 

分 类 号：R978.11[医药卫生—药品] R969.3[医药卫生—药学]