386例新生儿脐血乙肝标志物检测  

Detection on cord blood markers of hepatitis B in 386 neonates

作　　者：伏钢[1] 彭艳华[1] 李毅刚[1] 曾蕾[1] 

机构地区：[1]湖南省劳动卫生职业病防治所检验科,湖南长沙410007

出　　处：《现代预防医学》2013年第2期238-239,共2页Modern Preventive Medicine

摘　　要：目的检测乙肝表面抗原阳性孕产妇脐带血标本乙肝标志物,分析乙肝宫内感染情况。方法将HBsAg阳性产妇分为"HBsAg阳性、HBeAg阴性"组与"HBsAg阳性、HBeAg阳性"组,对其脐带血进行乙肝标志物检测。结果新生儿脐带血HBsAg阳性30例,宫内感染率7.8%,"HBsAg阳性、HBeAg阴性"孕产妇组新生儿宫内感染率4.9%,"HBsAg阳性、HBeAg阳性"孕产妇组新生儿宫内感染率16.0%,两组新生儿宫内感染率差异有统计学意义(χ2=12.75,P﹤0.01)。结论 "HBsAg阳性、HBeAg阳性"的孕产妇更容易发生宫内感染,应采取积极的治疗措施,以降低母婴传播的机率。OBJECTIVE To detect the HBV markers of maternal woman who were patients of HBsAg positive, to analyze the intrauterine infection condition of HBV Method HBsAg positive puerperas were divided into ＂HBsAg positive, HBeAg negative＂ group and ＂HBsAg positive, HBeAg positive＂ group, HBV markers were detected in umbilical cord blood. RESULTS The cases of HbsAg positive in umbilical cord blood were 30 cases and intrauterine infection rate was 7.8%, the intrauterine infection rate was 4.9% in ＂HBsAg positive, HBeAg negative＂ group, and it was 16.0% in ＂HBsAg positive, HBeAg positive＂ group. There was a significant difference in the two groups （χ^2 = 12.75, P 〈 0.01）. CONCLUSION Both HBsAg and HBeAg positive women are more likely to have intrauterine infection, we should take actively measures to reduce the probability of HBV transmission.

关 键 词：脐带血 乙型肝炎 宫内感染 

分 类 号：R496.6[医药卫生—康复医学]