独子藤茎的化学成分研究  

Study on Chemical Constituents from the Stems of Celastrus monospermus

作　　者：陈铭祥[1] 喻文进[2] 林晓[1] 李尚德[1] 王定勇[2] 

机构地区：[1]广东医学院化学与药学实验教学中心,广东东莞523808 [2]广东药学院药科学院,广州510006

出　　处：《中国药房》2013年第3期259-261,共3页China Pharmacy

基　　金：广东医学院科研项目(Q2011006)资助

摘　　要：目的:研究独子藤茎的化学成分。方法:采用溶剂提取、硅胶柱色谱及结晶法对独子藤进行化学成分的分离,通过理化性质和波谱分析鉴定其结构。结果:从独子藤茎中分离并鉴定出7个化合物,分别为齐墩果烯(1)、3-氧代木栓烷(2)、3-氧代木栓烷-28-醛(3)、3,12-二氧代木栓烷(4)、3-氧代-28-羟基木栓烷(5)、3-氧代-11β-羟基木栓烷(6)、3-氧代-12α-羟基木栓烷(7)。其中,化合物1、4、5、6、7均为首次从该植物茎中分离得到。结论:本研究结果可为开发和利用独子藤植物资源提供借鉴和参考。OBJECTIVE：To study the chemical constituents from the stems of Celastrus monospermus.METHODS：The constituents were extracted with ethyl acetate,and isolated and purified by silica gel column chromatography and crystallization.Their structures were elucidated by physico-chemical properties and spectroscopic data.RESULTS：7 compounds were isolated from this plant,and they were identified as oleanolic alkene（1）,friedelane-3-one（2）,friedelane-3-on-28-al（3）,friedelane-3,12-dione（4）,28-hydroxyfriedelane-3-one（5）,11β-hydroxy-friedelane-3-one（6）,12α-hydroxy-friedelane-3-one（7）.Compounds 1,4,5,6,7 were obtained from the stems of this plant for the first time.CONCLUSION：The study provide reference for development and utilization of C.monospermus.

关 键 词：独子藤 化学成分 成分分离 鉴定 木栓烷型三萜类化合物 

分 类 号：R284.1[医药卫生—中药学] R917[医药卫生—中医学]