慢性哮喘患者缓解期血清干扰素测定  

The Measurement of Serum Interferon in the Chronic Bronchial Asthma

作　　者：李京培[1] 史百芬[1] 阎怀士[2] 许迪威[3] 

机构地区：[1]安徽医科大学微生物学教研室 [2]省立医院中医科 [3]省立医院内科

出　　处：《安徽医科大学学报》1991年第2期88-89,共2页Acta Universitatis Medicinalis Anhui

摘　　要：采用微量病变细胞抑制法对51例慢性哮喘患者进行了血清干扰素水平测定。捡测发现慢性哮喘缓解组31例(60.8%)IFN≥1.0×10~3IU/L,20例(39.2%)<1.0×10~3IU/L明显低于正常人(2.230±0.447×10~3IU/L)。IFN水平与慢性哮喘病程和病毒等反复感染有一定关系,故IFN水平测定有可能作为观察慢性哮喘患者免疫调节功能的指标。The level of serum interferon(IFN)in 51 patients with chronic bronchial asthma by microdetermination were investigated, it was found that among 51 patients in remission stage, in 31 cases (60.8%)IFN≥1.0×10~3IU/L and in 20 cases(39.2%)INF<1.0×10~3IU/L. The IFN level in asthma patients is obviously lower than that in normal control(2.230±0.447×10~8IU/L). IFN level was related to the disease-process and recurrent infections of virus. The diminished level of IFN in asthma was similar to that in some other viral infections disease. It was suggested that the measurement of IFN level might be used as an indictor to observe the immunity regulation in patients with chronic bronchial asthma and it was worth further investigating.

关 键 词：哮喘 干扰素 免疫学 

分 类 号：R562.250.3[医药卫生—呼吸系统]