抗菌性大分子紫外线吸收剂的合成及性能  

Synthesis and properties of water-soluble macromolecular UV absorber with antimicrobial property

作　　者：马威[1] 白晓娟[1] 拓婷婷[1] 刘勇[1] 张淑芬[1] 

机构地区：[1]大连理工大学精细化工国家重点实验室,辽宁大连116023

出　　处：《中国科技论文》2012年第12期917-920,934,共5页China Sciencepaper

基　　金：国家自然科学基金资助项目(20806013;20923006);国家科技支撑计划资助项目(2011BAE07B08);高等学校博士学科点专项科研基金资助项目(200801411011)

摘　　要：以2-羟基二苯甲酮为紫外线吸收功能基,以聚乙烯胺(PVAm)为大分子骨架和抗菌功能基,合成了兼具抗菌功能的水溶性大分子紫外线吸收剂PVAm-g-UV-0。PVAm-g-UV-0的制备分两步,首先在2,4-二羟基二苯甲酮(UV-0)结构中引入环氧基,制备反应中间体2-羟基-4(2,3-环氧丙氧基)二苯甲酮(Epoxy-UV-0);然后通过环氧基与PVAm侧链上的氨基反应,将UV-0引入PVAm,合成目标大分子PVAm-g-UV-0。并优化了溶剂比、加碱量、反应温度、投料量等反应条件。PVAm-g-UV-0经过FT-IR、UV吸收光谱分析证明2-羟基二苯甲酮结构已连接到PVAm上。性能测试显示制备的功能分子PVAm-g-UV-0不但在紫外区具有广泛的吸收,而且具有良好的抑菌性。A novel water-soluble macromolecular ullraviolet absorber PVAm-g-UV-0 with antimicrobial property has been designed and synthesized with 2-hydmxybenzophenone as UV absorbing group and polyvinylamine （PVAm） as antimicrobial functional compounds and grafting backbone. PVAm-g-UV-0 was synthesized through two steps. Epoxy group was first introducd to 2,4- dihydroxybenzophenone to prepare the intermediate 2-hydroxy-4（2,3-epoxypmpoxy）-benzophenone. Then the intermediate was introduced to PVAm through reaction of the epoxy group and the amino group of PVAm to yield the target product PVAm-g-UV-0. The conditions for preparing the product were optimized by studying the solvent ratio, addition of alkali, reaction temperature, dosage of reactant, etc. 2-hydmxybenzophenone was confirmed to be grafted onto PVAm through IR and UV spectroscopy Performance test shows that PVAm-g-UV-0 has wide adsorption within UV area and good antimicrobial property.

关 键 词：水溶性紫外线吸收剂 聚乙烯胺 二苯甲酮 抗菌 

分 类 号：TQ424[化学工程]