新型单铆双盘状封堵器治疗动脉导管未闭的安全性和疗效观察  

New type single-rivet double-plate occluder device for the treatment of patent ductus arteriosus:its clinical safety and therapeutic observation

作　　者：游晓华[1] 王可[1] 陈少萍[1] 李松华[1] 陈峰[1] 熊文峰[1] 赵仙先[1] 秦永文[1] 

机构地区：[1]第二军医大学长海医院心血管内科,上海200433

出　　处：《介入放射学杂志》2013年第1期12-14,共3页Journal of Interventional Radiology

摘　　要：目的评价新型单铆双盘状封堵器治疗动脉导管未闭的安全性及疗效。方法收集动脉导管未闭患者47例,按选用封堵器的类型不同分为试验组31例,植入新型单铆双盘状封堵器(Sunflower封堵器),对照组16例,植入双盘状封堵器(SHSMA封堵器)。记录两组患者的年龄、体重、植入封堵器大小,右室收缩、舒张、平均压,肺动脉收缩、舒张、平均压及主动脉收缩、舒张、平均压和并发症发生率,术后随访心电图,术后1、3、6个月随访经胸超声心动图。结果 47例患者手术全部成功,手术成功率为100%。试验组植入封堵器腰部直径为5～18 mm,平均(11.7±3.6)mm;对照组植入封堵器腰部直径为6～16 mm,平均(11.0±3.3)mm。试验组患者术后均无并发症发生;心电图左心室负荷增大明显改善,彩色多普勒超声随访未见残余分流。对照组有1例术中出现高血压危象,1例术后血小板减少,1例术后3个月内存在残余分流,心电图及术后6个月的随访对照组与试验组差异均无统计学意义(P>0.05)。结论 Sunflower封堵器治疗动脉导管未闭安全、有效。Objective To assess the clinical safety and efficiency of new type single-rivet double- plate oceluder device in treating patent ductus arteriosu （PDA）. Methods A total of forty-seven patients with PDA were collected for this study. According to the occluder type used in the treatment, the patients were divided into study group （n = 31） and control group （n = 16）. Implantation of new type single-rivet double-plate occluder device （sunflower occluder） was carried out in the patients of study group, while SHSMA oceluder was employed in the patients of control group. Patient＇s age, body weight, occluder size, the systolic, diastolic and mean pressure of the right ventricle, the systolic, diastolic and mean pressure of the pulmonary artery, the systolic, diastolic and mean pressure of the aorta, and the occurrence of complications were documented. The results were analyzed. Follow- up checkups with electrocardiogram （ECG） and trans-thoraeie echoeardiography at one, 3 and 6 months after the treatment were carried out. Results Technical success was obtained in all patients. In the study group, the waist diameter of the implanted occluder was （5 - 18） mm, with a mean diameter of （11.7 ± 3.6） mm. In the control group, the waist diameter of the implanted occluder was （6 - 16） ram, with a mean diameter of （11.0 ± 3.3） ram. No complications occurred in the study group. After the treatment, obvious improvement of left ventricle aggravated load was seen on ECG, and no residual shunt was found on Doppler ultrasound echocardiography. In the control group, hypertensive crisis occurred in one patient, thromboeytopenia occurred in another patient, and residual shunt was found in one patient within three months after the treatment. ConclusionFor the treatment of PDA, the use of the new type single-rivet double-plate occluder device （sunflower occluder） is safe andeffective. （J Intervent Radiol, 2013, 22： 012-014）

关 键 词：动脉导管未闭 新型单铆双盘状封堵器 疗效 

分 类 号：R541.1[医药卫生—心血管疾病]