几丁糖和透明质酸钠防粘连材料在妇产科的应用  

Application of chitosan and sodium hyaluronate anti-adhesion materials in the obstetrics and gynecology

作　　者：王莲莲[1] 曹霞[1] 罗希[1] 施展[1] 

机构地区：[1]中国医科大学附属第四医院,辽宁省沈阳市110032

出　　处：《中国组织工程研究》2012年第47期8923-8930,共8页Chinese Journal of Tissue Engineering Research

摘　　要：背景:妇产科防粘连材料的应用可避免再次给患者造成痛苦和伤害,减少不孕、肠梗阻等其它相关并发症的发生,目的:分析在妇产科各种防粘连材料临床应用的效果,为防粘连材料的临床应用选择提供可参考借鉴的理论信息。方法:对不同防粘连材料妇产科的临床应用效果进行分析,采用动物模型试验和临床病例随访的方法,重点分析几丁糖和透明质酸钠用于多种妇产科疾病防粘连治疗时的选择应用范围及效果。结果与结论:妇产科临床应用防粘连材料可以获得满意的效果,医用生物膜、玻璃酸钠、聚乳酸凝胶等也可用于妇产科防粘连的应用,但是相比而言,几丁糖和透明质酸钠的防粘连效果更优异。BACKGROUND： The application of anti-adhesion materials in obstetrics and gynecology can avoid causing pain and injury to the patients again, and can reduce the incidence of infertility, bowel obstruction and other complications. OBJECTIVE： To analyze the effect of various anti-adhesion materials in obstetrics and gynecology, in order to provide the theoretical information for the clinical application and selection of anti-adhesion materials. METHODS： The effects of different anti-adhesion materials applied in the obstetrics and gynecology were analyzed, to analyze the application range and effects of chitosan and sodium hyalurenate in the anti-adhesion treatment of various obstetric and gynecological diseases. RESULTS AND CONCLUSION： The clinical application of anti-adhesion materials in obstetrics and gynecologyo can obtain satisfactory results, and the medical biofilm, sodium hyaluronate and polylactic acid gel can also be used for the anti-adhesion treatment in obstetrics and gynecologyo. However, chitosan has a more excellent anti-blocking effect compared with sodium hyaluronate.

关 键 词：妇产科 防粘连 几丁糖 透明质酸钠 医用生物膜 生物材料 宫腔粘连 盆腔粘连 腹腔粘连 肠粘连 肠梗阻 

分 类 号：R318[医药卫生—生物医学工程]