肾素-血管紧张素系统阻断剂在慢性肾病治疗中的应用  

Application of renin-angiontensin system blockers in chronic kidney disease treatment

作　　者：陈颖颖[1] 丁峰[1] 

机构地区：[1]复旦大学附属华山医院肾脏科,上海200040

出　　处：《上海医药》2013年第1期5-9,共5页Shanghai Medical & Pharmaceutical Journal

基　　金：国家自然科学基金项目(项目编号:81070609);国家自然科学基金项目(项目编号:81270850);上海市科学技术委员会重点项目(项目编号:11441901400)

摘　　要：延缓慢性肾病的进展、阻止终末期肾病的发生是肾脏病学领域的研究热点。阻断肾素-血管紧张素系统(RAS)能较有效地降低血压和减少尿蛋白的排出,从而达到保护肾脏、阻止肾病慢性进展的目的。本文主要介绍几种常用的RAS阻断剂对肾脏的保护作用、在慢性肾病治疗中的应用以及常见不良反应。To delay the progression of chronic kidney disease and prevent the occurrence of end stage renal disease are a research focus in the field of nephrology. Blocking the renin-angiotensin system can effectively lower the blood pressure and reduce the output of urine protein so as to attain the target of protecting the kidney and preventing kidney disease chronic progress. This paper introduces the protective effects of kidney, applications and the common adverse drug reactions of several commonly used rennin-angiontensin system blockers in the treatment of chronic kidney disease.

关 键 词：慢性肾病 肾素-血管紧张素系统 终末期肾病 

分 类 号：R692.9[医药卫生—泌尿科学]